An improved one-pot cost-effective synthesis of N,N-disubstituted carbamoyl halides and derivatives

被引：6
|
作者：
Adeppa, K. [2 ]
Rupainwar, D. C. [2 ]
Misra, Krishna [1 ]
机构：
[1] Indian Inst Informat Technol, Allahabad 211002, Uttar Pradesh, India
[2] UP Tech Univ, Lucknow 226000, Uttar Pradesh, India
来源：
CANADIAN JOURNAL OF CHEMISTRY | 2010年 / 88卷 / 12期
关键词：
carbonylsulfenyl chloride; secondary amines; dichloromethane; carbamoyl halides; CHLORIDES;
D O I：
10.1139/V10-138
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A convenient one-pot procedure is reported for preparing N,N-disubstituted carbamoyl chlorides by using chlorocarbonylsulfenyl chloride as a carbonylating agent. It comprises the reaction of secondary amines with chlorocarbonylsulfenyl chloride in the presence of an aprotic organic solvent to produce the corresponding N,N-disubstituted carbamoyl halides. Insertion of the carbonyl group without using phosgene is the novelty of this method.
引用
收藏
页码：1277 / 1280
页数：4
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