Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa

被引：43

作者：

Shah, N. Sarita ^{[1
,2
,3
]}

Richardson, Jessica ^{[2
,3
]}

Moodley, Prashini ^{[4
]}

Moodley, Salona ^{[4
]}

Babaria, Palav ^{[2
,5
]}

Ramtahal, Melissa ^{[4
]}

Heysell, Scott K. ^{[2
]}

Li, Xuan ^{[3
]}

Moll, Anthony P. ^{[2
,6
]}

Friedland, Gerald ^{[2
,5
]}

Sturm, A. Willem ^{[4
]}

Gandhi, Neel R. ^{[2
,3
]}

机构：

[1] Albert Einstein Coll Med, Dept Med, Bronx, NY 10467 USA

[2] Tugela Ferry Care & Res Collaborat, Tugela Ferry, South Africa

[3] Montefiore Med Ctr, Bronx, NY 10467 USA

[4] Nelson R Mandela Sch Med, Durban, South Africa

[5] Yale Univ, New Haven, CT USA

[6] Philanjalo Care Ctr, Tugela Ferry, South Africa

来源：

EMERGING INFECTIOUS DISEASES | 2011年 / 17卷 / 03期

关键词：

EMERGENCE;

D O I：

10.3201/eid1703.101363

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We expanded second-line tuberculosis (TB) drug susceptibility testing for extensively drug-resistant Mycobacterium tuberculosis isolates from South Africa. Of 19 patients with extensively drug-resistant TB identified during February 2008 April 2009, 13 (68%) had isolates resistant to all 8 drugs tested. This resistance leaves no effective treatment with available drugs in South Africa.

引用

页码：510 / 513

页数：4

共 12 条

[1]

[Anonymous], 2010, WHO/HTM/TB/2010.3

[2] Emergence of Increased Resistance and Extensively Drug-Resistant Tuberculosis Despite Treatment Adherence, South Africa [J].

Calver, Alistair D. ;

Falmer, Alecia A. ;

Murray, Megan ;

Strauss, Odelia J. ;

Streicher, Elizabeth M. ;

Hanekom, Madelene ;

Liversage, Thelma ;

Masibi, Mothusi ;

van Helden, Paul D. ;

Warren, Robin M. ;

Victor, Thomas C. .

EMERGING INFECTIOUS DISEASES, 2010, 16 (02) :264-271

[3] Emergence of Extensive Drug Resistance during Treatment for Multidrug-Resistant Tuberculosis [J].

Cox, Helen S. ;

Sibilia, Katia ;

Feuerriegel, Silke ;

Kalon, Stobdan ;

Polonsky, Jonny ;

Khamraev, Atadjan K. ;

Ruesch-Gerdes, Sabine ;

Mills, Clair ;

Niemann, Stefan .

NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (22) :2398-2400

[4] Extensively drug-resistant tuberculosis as a cause of death in patients co-infected with tuberculosis and HIV in a rural area of South Africa [J].

Gandhi, Neel R. ;

Moll, Anthony ;

Sturm, A. Willem ;

Pawinski, Robert ;

Govender, Thiloshini ;

Lalloo, Umesh ;

Zeller, Kimberly ;

Andrews, Jason ;

Friedland, Gerald .

LANCET, 2006, 368 (9547) :1575-1580

[5] Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis [J].

Gandhi, Neel R. ;

Nunn, Paul ;

Dheda, Keertan ;

Schaaf, H. Simon ;

Zignol, Matteo ;

van Soolingen, Dick ;

Jensen, Paul ;

Bayona, Jaime .

LANCET, 2010, 375 (9728) :1830-1843

[6] HIV Coinfection in Multidrug- and Extensively Drug-Resistant Tuberculosis Results in High Early Mortality [J].

Gandhi, Neel R. ;

Shah, N. Sarita ;

Andrews, Jason R. ;

Vella, Venanzio ;

Moll, Anthony P. ;

Scott, Michelle ;

Weissman, Darren ;

Marra, Claudio ;

Lalloo, Umesh G. ;

Friedland, Gerald H. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2010, 181 (01) :80-86

[7]

Kam KM, 2010, INT J TUBERC LUNG D, V14, P282

[8]

Laserson KF, 2005, INT J TUBERC LUNG D, V9, P640

[9] Comprehensive treatment of extensively drug-resistant tuberculosis [J].

Mitnick, Carole D. ;

Shin, Sonya S. ;

Seung, Kwonjune J. ;

Rich, Michael L. ;

Atwood, Sidney S. ;

Furin, Jennifer J. ;

Fitzmaurice, Garrett M. ;

Alcantara Viru, Felix A. ;

Appleton, Sasha C. ;

Bayona, Jaime N. ;

Bonilla, Cesar A. ;

Chalco, Katiuska ;

Choi, Sharon ;

Franke, Molly F. ;

Fraser, Hamish S. F. ;

Guerra, Dalia ;

Hurtado, Rocio M. ;

Jazayeri, Darius ;

Joseph, Keith ;

Llaro, Karim ;

Mestanza, Lorena ;

Mukherjee, Joia S. ;

Munoz, Maribel ;

Palacios, Eda ;

Sanchez, Epifanio ;

Sloutsky, Alexander ;

Becerra, Mercedes C. .

NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (06) :563-574

[10] Treatment outcomes among patients with multidrug-resistant tuberculosis: systematic review and meta-analysis [J].

Orenstein, Evan W. ;

Basu, Sonjay ;

Shah, N. Sarita ;

Andrews, Jason R. ;

Friedland, Gerald H. ;

Moll, Anthony P. ;

Gandhi, Neel R. ;

Galvani, Alison P. .

LANCET INFECTIOUS DISEASES, 2009, 9 (03) :153-161

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