Survival and transmission of community-associated methicillin-resistant Staphylococcus aureus from fomites

被引：71
作者：
Desai, Rishi [1 ]
Pannaraj, Pia S. [1 ,2 ]
Agopian, Jaclyn [2 ]
Sugar, Catherine A. [3 ]
Liu, George Y. [4 ]
Miller, Loren G. [5 ,6 ,7 ]
机构：
[1] Childrens Hosp Los Angeles, Div Pediat Infect Dis, Los Angeles, CA 90027 USA
[2] Univ So Calif, Keck Sch Med, Los Angeles, CA 90033 USA
[3] Univ Calif Los Angeles, Sch Publ Hlth, Los Angeles, CA 90024 USA
[4] Cedars Sinai Hlth Syst, Los Angeles, CA USA
[5] Harbor UCLA Med Ctr, Div Infect Dis, Los Angeles, CA USA
[6] Harbor UCLA Med Ctr, Los Angeles Biomed Res Inst, Los Angeles, CA USA
[7] Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90095 USA
来源：
AMERICAN JOURNAL OF INFECTION CONTROL | 2011年 / 39卷 / 03期
关键词：
Transmission; fomites; methicillin-resistant Staphylococcus aureus; SOFT-TISSUE INFECTIONS; SKIN INFECTIONS; FOOTBALL TEAM; VIRULENCE; FABRICS; RESERVOIRS; EVOLUTION; OUTBREAK; SURFACES; BACTERIA;
D O I：
10.1016/j.ajic.2010.07.005
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Background: Transmission of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) from fomites appears to play an important role in CA-MRSA outbreaks. However, the amount and duration of transmissibility of MRSA have not been quantified. Methods: We assessed the survival and transmission of the CA-MRSA strain USA300-0114 from 9 fomites (razors, plastic toys, ceramic, soap, wood, vinyl, towels, bed sheets, and shoulder pads). Fomites were inoculated then briefly pressed onto sterile pigskin at 5 minutes; days 1, 2, 3, 7, and 10; and then weekly for 10 weeks. The experiment was repeated using 2 methicillin-susceptible S aureus (MSSA) and 3 health care-associated (HA) MRSA strains on select fomites. Result: Bacteria could be transmitted to skin from all fomites except soap. Transmissibility decreased over time but more rapidly from porous (eg, towels) than nonporous (eg, vinyl) fomites (P = .0002), with some fomites showing transmissibility for more than 8 weeks after contamination. The CA-MRSA strain was transmissible longer than the HA-MRSA strains (P < .0001) and 1 MSSA strain. Conclusion: CA-MRSA strains are transmissible from many fomites to skin with contaminated nonporous fomites exhibiting transmissibility many weeks after contamination. Transmissibility of HA-MRSA strains demonstrated attenuated transmissibility compared with CA-MRSA strains. Findings may have implications for CA-MRSA infection prevention.
引用
收藏
页码：219 / 225
页数：7
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