The receptor of the type I interferon family

被引：0
|
作者：
Uze, G. [1 ]
Schreiber, G. [2 ]
Piehler, J. [3 ]
Pellegrini, S. [4 ]
机构：
[1] Univ Montpellier 2, CNRS, UMR 5124, F-34095 Montpellier 5, France
[2] Weizmann Inst Sci, Dept Biol Chem, IL-76100 Rehovot, Israel
[3] Goethe Univ Frankfurt, Inst Biochem, Bioctr N210, D-60439 Frankfurt, Germany
[4] Inst Pasteur, CNRS, URA 1961, Unit Cytokine Signaling, F-75015 Paris, France
来源：
INTERFERON: THE 50TH ANNIVERSARY | 2007年 / 316卷
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
All type I IFNs act through a single cell surface receptor composed of the IFNAR1 and IFNAR2 subunits and two associated cytoplasmic tyrosine kinases of the Janus family, Tyk2 and Jak1. A central issue in type I IFN biology is to understand how 1 a multitude of subtypes can generate similar signaling outputs but also govern specific 1 cellular responses. This review summarizes results from the last decade that contributed to our current state of knowledge of IFN-receptor complex structure and assembly.
引用
收藏
页码：71 / 95
页数：25
相关论文
共 50 条
  • [21] Who will respond to type I interferon receptor blockade in SLE?
    Aringer, Martin
    LANCET RHEUMATOLOGY, 2022, 4 (04): : E234 - E236
  • [22] Expression of type I interferon receptor in solid tumors of childhood
    Rosolen, A
    Todesco, A
    Colamonici, OR
    Basso, G
    Frascella, E
    MODERN PATHOLOGY, 1997, 10 (01) : 55 - 61
  • [23] Type I interferon receptor assembling on supported lipid bilayers
    Pichler, J
    Lata, S
    Gavutis, M
    Lamken, P
    Mueller, P
    PROTEIN SCIENCE, 2004, 13 : 187 - 187
  • [24] Dynamics of the Type I interferon receptor assembly in the plasma membrane
    Wilmes, Stephan
    Loechte, Sara
    Beutel, Oliver
    You, Changjiang
    Richter, Christian Paolo
    Piehler, Jacob
    EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2011, 40 : 223 - 223
  • [25] Multifaceted Activities of Type I Interferon Are Revealed by a Receptor Antagonist
    Levin, Doron
    Schneider, William M.
    Hoffmann, Hans-Heinrich
    Yarden, Ganit
    Busetto, Alberto Giovanni
    Manor, Ohad
    Sharma, Nanaocha
    Rice, Charles M.
    Schreiber, Gideon
    SCIENCE SIGNALING, 2014, 7 (327)
  • [26] Interferon-alpha/beta receptor-independent type I interferon production
    Hocker, Lena
    Bedenbender, Katrin
    Riegger, David
    Lienenklaus, Stefan
    Scheu, Stefanie
    Kochs, Georg
    Waibler, Zoe
    CYTOKINE, 2015, 76 (01) : 78 - 78
  • [27] Type I interferon structures: Possible scaffolds for the interferon-alpha receptor complex
    Nagabhushan, Tattanahalli L.
    Reichert, Paul
    Walter, Mark R.
    Murgolo, Nicholas J.
    2002, National Research Council of Canada (80)
  • [28] Type I Interferon Receptor on NK Cells Negatively Regulates Interferon-γ Production
    Lee, Amanda J.
    Mian, Firoz
    Poznanski, Sophie M.
    Stackaruk, Michele
    Chan, Tiffany
    Chew, Marianne V.
    Ashkar, Ali A.
    FRONTIERS IN IMMUNOLOGY, 2019, 10
  • [29] Type I interferon structures: Possible scaffolds for the interferon-alpha receptor complex
    Nagabhushan, TL
    Reichert, P
    Walter, MR
    Murgolo, NJ
    CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 2002, 80 (08): : 1166 - 1173
  • [30] The human type I interferon receptor - Identification of the interferon beta-specific receptor-associated phosphoprotein
    Croze, E
    RussellHarde, D
    Wagner, TC
    Pu, HF
    Pfeffer, LM
    Perez, HD
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (52) : 33165 - 33168
12345