Evolution of antiglomerular basement membrane glomerulonephritis into membranous glomerulonephritis

被引：11
|
作者：
Hecht, Natalie [2 ]
Omoloja, Abiodun [2 ]
Witte, Dave [3 ]
Canessa, Leonardo [1 ,2 ]
机构：
[1] Childrens Med Ctr, Dept Nephrol, Dayton, OH 45404 USA
[2] Wright State Univ, Boonshoft Sch Med, Dept Pediat, Dayton, OH 45435 USA
[3] Univ Cincinnati, Dept Pathol, Cincinnati, OH USA
来源：
PEDIATRIC NEPHROLOGY | 2008年 / 23卷 / 03期
关键词：
anti-GBM antibody; membranous glomerulonephritis;
D O I：
10.1007/s00467-007-0639-3
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Antiglomerular basement membrane glomerulonephritis (anti-GBM GN) is a rare disease characterized by autoantibodies to the alpha 3 chain of type IV collagen in the GBM. It is also known as Goodpasture's syndrome when associated with pulmonary hemorrhage due to autoantibodies to the alpha 3 chain of type IV collagen also present in pulmonary alveoli. Even more rare is the evolution of anti-GBM GN into membranous nephropathy (MN). We report the management of a 9-year-old Caucasian girl with anti-GBM GN that evolved into MN and briefly review the literature.
引用
收藏
页码：477 / 480
页数：4
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