Hydrolytic cleavage of DNA by a ruthenium(II) polypyridyl complex

被引：66

作者：

Deshpande, Megha S. ^{[1
]}

Kumbhar, Anupa A. ^{[1
]}

Kumbhar, Avinash S. ^{[1
]}

机构：

[1] Univ Pune, Dept Chem, Pune 4110079, Maharashtra, India

来源：

INORGANIC CHEMISTRY | 2007年 / 46卷 / 14期

关键词：

D O I：

10.1021/ic070331d

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The complex [Ru(bpy)(2)(BPG)]Cl-2 containing hydrogen-bond donor (N-H atoms) and acceptor (O atoms) groups mediates hydrolytic cleavage of plasmid pBR322 DNA in an enzyme-like manner. The kinetic aspects of DNA cleavage under pseudo- and true-Michaelis-Menten conditions are detailed.

引用

页码：5450 / 5452

页数：3

共 41 条

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