A neurocomputational approach to obsessive-compulsive disorder

被引:13
作者
Maia, Tiago V. [1 ,2 ,3 ]
McClelland, James L. [4 ,5 ]
机构
[1] Columbia Univ, Dept Psychiat, New York, NY 10032 USA
[2] New York State Psychiat Inst & Hosp, Unit 78, New York, NY 10032 USA
[3] Univ Lisbon, Fac Med, Inst Physiol, P-1649028 Lisbon, Portugal
[4] Stanford Univ, Dept Psychol, Stanford, CA 94305 USA
[5] Stanford Univ, Ctr Mind Brain & Computat, Stanford, CA 94305 USA
关键词
SCHIZOPHRENIA; DOPAMINE; MODELS; CORTEX;
D O I
10.1016/j.tics.2011.11.011
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
A recent article shows that a change in a single parameter in a neural-network model of brain dynamics leads to repetitive behaviors that resist termination and towards which the network tends. These findings may have implications for obsessive-compulsive disorder and are consistent with evidence of glutamatergic hyperactivity in this disorder.
引用
收藏
页码:14 / 15
页数:2
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