Waveform optimization for internal atrial defibrillation: Effects of waveform rounding, phase duration, and voltage swing

被引:8
作者
Kidwai, BJ
Allen, JD
Harbinson, MT
Mcintyre, A
Anderson, J
Adgey, AAJ
机构
[1] Queens Univ Belfast, Royal Victoria Hosp, Reg Med Cardiol Ctr, Belfast BT12 6BA, Antrim, North Ireland
[2] Queens Univ Belfast, Dept Physiol, Belfast BT12 6BA, Antrim, North Ireland
[3] Univ Ulster, No Ireland Bioengn Ctr, Jordanstown, North Ireland
来源
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY | 2001年 / 24卷 / 08期
关键词
atrial defibrillation; internal; waveform rounding; biphasic waveforms;
D O I
10.1046/j.1460-9592.2001.01198.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The aim of this study was to compare the efficacy of internal atrial defibrillation by conventional truncated exponential biphasic waveforms with and without waveform rounding (1-2 phases) and to determine optimal duration for this novel double rounded waveform. A trial fibrillation, induced by rapid electrical stimulation, was converted by internal shocks through defibrillation catheters (lateral right atrium and coronary sinus) in anesthetised sheep. Rounding the leading edges of the conventional biphasic waveform (Ventritex HVS-02; settings 100/-50 V, 150/-70 V, and 200/-100 V, n = 8) reduced delivered peak and trough voltages, currents, and energy (by greater than or equal to 21%, P < 0.001; for double (both phases) rounded) without decreasing cardioversion success. At 100/-50 V the efficacy of single (first phase) rounded (53<plus/minus>13%; mean +/- SEM) and double rounded (59 +/- 11%) shocks was similar to the conventional waveform (56 +/- 14%). Double rounded waveform (phase durations 1-20 ms) efficacy was optimum at 6-10 ms phase duration (100% success at 10-ms phase duration; 1.52 +/-0.04 J delivered energy, n = 6). Successful cardioversion by conventional, single rounded, and double rounded biphasic waveforms (duration 6 ms each phase), conventional monophasic, rounded monophasic (duration 12 ms), and a damped sine waveform correlated strongly with peak-to-trough voltage swing within the waveform (r = 0.882; P < 0.01; n = 8). For internal atrial defibrillation, rounding both phases of the conventional biphasic waveforms, the double rounded waveform, permits similar efficacy to the conventional truncated exponential biphasic waveform at reduced peak voltage, current, and delivered energy. Optimum phase duration is 6-10 ms (tested range 1-20 ms).
引用
收藏
页码:1198 / 1207
页数:10
相关论文
共 20 条
[1]   INITIAL EXPERIENCE WITH INTRACARDIAC ATRIAL DEFIBRILLATION IN PATIENTS WITH CHRONIC ATRIAL-FIBRILLATION [J].
ALT, E ;
SCHMITT, C ;
AMMER, R ;
COENEN, M ;
FOTUHI, P ;
KARCH, M ;
BLASINI, R .
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 1994, 17 (05) :1067-1078
[2]   Pain threshold for low energy intracardiac cardioversion of atrial fibrillation with low or no sedation [J].
Ammer, R ;
Alt, E ;
Ayers, G ;
Schmitt, C ;
Pasquantonio, J ;
Schmidt, M ;
Putter, K ;
Schomig, A .
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 1997, 20 (01) :230-236
[3]   A PROSPECTIVE RANDOMIZED EVALUATION OF BIPHASIC VERSUS MONOPHASIC WAVEFORM PULSES ON DEFIBRILLATION EFFICACY IN HUMANS [J].
BARDY, GH ;
IVEY, TD ;
ALLEN, MD ;
JOHNSON, G ;
MEHRA, R ;
GREENE, HL .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1989, 14 (03) :728-733
[4]   STRENGTH-DURATION CURVES OF FIXED PULSE WIDTH VARIABLE TILT TRUNCATED EXPONENTIAL WAVEFORMS FOR NONTHORACOMY INTERNAL DEFIBRILLATION IN DOGS [J].
CHAPMAN, PD ;
WETHERBEE, JN ;
VETTER, JW ;
TROUP, P ;
SOUZA, J .
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 1988, 11 (07) :1045-1050
[5]  
Cheng YN, 1999, CIRC RES, V85, P1056
[6]  
Cooper RAS, 1997, CIRCULATION, V95, P1487
[7]   Marked reduction in internal atrial defibrillation thresholds with dual-current pathways and sequential shocks in humans [J].
Cooper, RAS ;
Plumb, VJ ;
Epstein, AE ;
Kay, GN ;
Ideker, RE .
CIRCULATION, 1998, 97 (25) :2527-2535
[8]   INTERNAL CARDIOVERSION OF ATRIAL-FIBRILLATION IN SHEEP [J].
COOPER, RAS ;
ALFERNESS, CA ;
SMITH, WM ;
IDEKER, RE .
CIRCULATION, 1993, 87 (05) :1673-1686
[9]   Rounded biphasic waveform reduces energy requirements for transvenous catheter cardioversion of atrial fibrillation and flutter [J].
Harbinson, MT ;
Allen, JD ;
Imam, Z ;
Dempsey, G ;
Anderson, JM ;
Ayers, GM ;
Adgey, AAJ .
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 1997, 20 (01) :226-229
[10]  
HARBINSON MT, 1997, THESIS QUEENS U BELF