Recommendations of the Brazilian Society of Rheumatology for the use of JAK inhibitors in the management of rheumatoid arthritis

被引：4

作者：

Bonfiglioli, Karina Rossi ^{[1
]}

da Mota, Licia Maria Henrique ^{[2
]}

de Medeiros Ribeiro, Ana Cristina ^{[1
]}

Kakehasi, Adriana Maria ^{[3
]}

Laurindo, Ieda Maria Magalhaes ^{[4
]}

Giorgi, Rina Dalva Neubarth ^{[5
]}

Duarte, Angela Luzia Branco Pinto ^{[6
]}

Reis, Ana Paula Monteiro Gomides ^{[2
]}

de Souza, Mariana Peixoto Guimaraes Ubirajara e Silva ^{[7
]}

Brenol, Claiton Viegas ^{[8
]}

da Rocha Castelar Pinheiro, Geraldo ^{[9
]}

de Albuquerque, Cleandro Pires ^{[2
]}

de Moura Castro, Charlles Heldan ^{[10
]}

Pinto, Gustavo Luiz Behrens ^{[11
]}

Verztman, Jose Fernando ^{[12
]}

Muniz, Luciana Feitosa ^{[13
]}

Bertolo, Manoel Barros ^{[14
]}

da Costa Pinto, Maria Raquel ^{[3
]}

Louzada Junior, Paulo ^{[15
]}

Cruz, Vitor Alves ^{[16
]}

Pereira, Ivanio Alves ^{[17
]}

de Freitas, Max Vitor Carioca ^{[18
]}

Cruz, Boris Afonso ^{[19
]}

Paiva, Eduardo ^{[20
]}

Monticielo, Odirlei ^{[8
]}

Provenza, Jose Roberto ^{[21
]}

Xavier, Ricardo Machado ^{[8
]}

机构：

[1] Univ Sao Paulo HC FMUSP, Fac Med, Disciplina Reumatol Hosp Clin, Av Dr Arnaldo,455-3 Andar Reumatol, BR-01246903 Sao Paulo, SP, Brazil

[2] Univ Brasilia HUB UnB, Serv Reumatol Hosp, Brasilia, DF, Brazil

[3] Univ Fed Minas Gerais UFMG, Serv Reumatol, Belo Horizonte, MG, Brazil

[4] Univ Nove Julho UNINOVE, Disciplina Reumatol, Sao Paulo, Brazil

[5] Hosp Servidor Publ Estadual Sao Paulo HSPE IAMSPE, Serv Reumatol, Sao Paulo, Brazil

[6] Univ Fed Pernambuco UFPE, Recife, PE, Brazil

[7] Santa Casa Belo Horizonte MG, Belo Horizonte, MG, Brazil

[8] Univ Fed Rio Grande Sul HCPA UFRGS, Hosp Clin Porto Alegre, Porto Alegre, RS, Brazil

[9] Univ Estado Rio De Janeiro UERJ, Rio De Janeiro, Brazil

[10] Univ Fed Sao Paulo, Escola Paulista Med, Sao Paulo, Brazil

[11] Univ Fed Bahia UFBA, Salvador, BA, Brazil

[12] Hosp Fed Servidores Estado RJ, Rio De Janeiro, Brazil

[13] Hosp Reg Sobradinho DF, Brasilia, DF, Brazil

[14] Univ Estadual Campinas, Fac Ciencias Med, Disciplina Reumatol, Campinas, Brazil

[15] Univ Sao Paulo USP RP, Fac Med Ribeirao Preto, Disciplina Reumatol, Ribeirao Preto, Brazil

[16] Univ Fed Goias, Fac Med, Disciplina Reumatol, Goiania, Go, Brazil

[17] Univ Fed Santa Catarina UFSC, Serv Reumatol, Hosp Univ, Florianopolis, SC, Brazil

[18] Univ Fortaleza UNIFOR, Fortaleza, Ceara, Brazil

[19] Pulsus Belo Horizonte MG, Belo Horizonte, MG, Brazil

[20] Univ Fed Parana UFPR, Disciplina Reumatol, Curitiba, Parana, Brazil

[21] Univ Catolica Campinas, PUC Campinas, Disciplina Reumatol Pontificia, Campinas, Brazil

来源：

ADVANCES IN RHEUMATOLOGY | 2021年 / 61卷 / 01期

关键词：

COST-EFFECTIVENESS ANALYSIS; INADEQUATE RESPONSE; TOFACITINIB CP-690,550; DOUBLE-BLIND; FILGOTINIB GLPG0634/GS-6034; BACKGROUND METHOTREXATE; JAPANESE PATIENTS; AMERICAN-COLLEGE; ZOSTER VACCINE; HERPES-ZOSTER;

D O I：

10.1186/s42358-021-00228-x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Rheumatoid arthritis (RA) is a chronic and autoimmune systemic inflammatory disease that can cause irreversible joint deformities, with increased morbidity and mortality and a significant impact on the quality of life of the affected individual. The main objective of RA treatment is to achieve sustained clinical remission or low disease activity. However, up to 40% of patients do not respond to available treatments, including bDMARDs. New therapeutic targets for RA are emerging, such as Janus kinases (JAKs). These are essential for intracellular signaling (via JAK-STAT) in response to many cytokines involved in RA immunopathogenesis. JAK inhibitors (JAKi) have established themselves as a highly effective treatment, gaining increasing space in the therapeutic arsenal for the treatment of RA. The current recommendations aim to present a review of the main aspects related to the efficacy and safety of JAKis in RA patients, and to update the recommendations and treatment algorithm proposed by the Brazilian Society of Rheumatology in 2017.

引用

页数：13

共 50 条

[1] Recommendations of the Brazilian Society of Rheumatology for the use of JAK inhibitors in the management of rheumatoid arthritis
Karina Rossi Bonfiglioli
Licia Maria Henrique da Mota
Ana Cristina de Medeiros Ribeiro
Adriana Maria Kakehasi
Ieda Maria Magalhães Laurindo
Rina Dalva Neubarth Giorgi
Angela Luzia Branco Pinto Duarte
Ana Paula Monteiro Gomides Reis
Mariana Peixoto Guimarães Ubirajara e Silva de Souza
Claiton Viegas Brenol
Geraldo da Rocha Castelar Pinheiro
Cleandro Pires de Albuquerque
Charlles Heldan de Moura Castro
Gustavo Luiz Behrens Pinto
Jose Fernando Verztman
Luciana Feitosa Muniz
Manoel Barros Bertolo
Maria Raquel da Costa Pinto
Paulo Louzada Júnior
Vitor Alves Cruz
Ivanio Alves Pereira
Max Vitor Carioca de Freitas
Bóris Afonso Cruz
Eduardo Paiva
Odirlei Monticielo
José Roberto Provenza
Ricardo Machado Xavier
Advances in Rheumatology, 61
[2] Recommendations by the Spanish Society of Rheumatology on risk management of biological treatment and JAK inhibitors in patients with rheumatoid arthritis
Balsa, Alejandro
Fontecha, Petra Diaz del Campo
Fernandez, Lucia Silva
Martin, Jose Valencia
Martinez, Virginia Nistal
Vazquez, Fernando Leon
Hernandez, M. Vanesa Hernandez
Corominas, Hector
Caliz, Rafael Caliz
Garcia, Jose Maria Aguado
Rodriguez, Gloria Candelas
Roteta, Nora Ibargoyen
Carvajal, Arturo Marti
Farras, M. Nieves Plana
Rioboo, Janet Punal
Park, Hye Sang
Pego, Yolanda Trinanes
Garcia, Virginia Villaverde
REUMATOLOGIA CLINICA, 2023, 19 (10): : 533 - 548
[3] 2017 recommendations of the Brazilian Society of Rheumatology for the pharmacological treatment of rheumatoid arthritis
Henrique da Mota, Licia Maria
Kakehasi, Adriana Maria
Monteiro Gomides, Ana Paula
Branco Pinto Duarte, Angela Luzia
Cruz, Boris Afonso
Brenol, Claiton Viegas
de Albuquerque, Cleandro Pires
Castelar Pinheiro, Geraldo da Rocha
Magalhaes Laurindo, Ieda Maria
Pereira, Ivanio Alves
Bertolo, Manoel Barros
Ubirajara Silva de Souza, Mariana Peixoto Guimaraes
Carioca de Freitas, Max Vitor
Louzada-Junior, Paulo
Xavier, Ricardo Machado
Neubarth Giorgi, Rina Dalva
ADVANCES IN RHEUMATOLOGY, 2018, 58
[4] 2017 recommendations of the Brazilian Society of Rheumatology for the pharmacological treatment of rheumatoid arthritis
Licia Maria Henrique da Mota
Adriana Maria Kakehasi
Ana Paula Monteiro Gomides
Angela Luzia Branco Pinto Duarte
Bóris Afonso Cruz
Claiton Viegas Brenol
Cleandro Pires de Albuquerque
Geraldo da Rocha Castelar Pinheiro
Ieda Maria Magalhães Laurindo
Ivanio Alves Pereira
Manoel Barros Bertolo
Mariana Peixoto Guimarães Ubirajara Silva de Souza
Max Vitor Carioca de Freitas
Paulo Louzada-Júnior
Ricardo Machado Xavier
Rina Dalva Neubarth Giorgi
Advances in Rheumatology, 58
[5] Recommendations of the German Rheumatology Society on the use of tocilizumab in rheumatoid arthritis
Gause, A.
Rubbert-Roth, A.
Michels, H.
Gaubitz, M.
Mayet, W. -J.
ZEITSCHRIFT FUR RHEUMATOLOGIE, 2010, 69 (04): : 365 - +
[6] Management of rheumatoid arthritis: consensus recommendations from the Hong Kong Society of Rheumatology
Mok, Chi Chiu
Tam, Lai Shan
Chan, Tak Hin
Lee, Gavin K. W.
Li, Edmund K. M.
CLINICAL RHEUMATOLOGY, 2011, 30 (03) : 303 - 312
[7] Management of rheumatoid arthritis: consensus recommendations from the Hong Kong Society of Rheumatology
Chi Chiu Mok
Lai Shan Tam
Tak Hin Chan
Gavin K. W. Lee
Edmund K. M. Li
Clinical Rheumatology, 2011, 30 : 303 - 312
[8] Recommendations of the French Society for Rheumatology for managing rheumatoid arthritis
Gaujoux-Viala, Cecile
Gossec, Laure
Cantagrel, Alain
Dougados, Maxime
Fautrel, Bruno
Mariette, Xavier
Nataf, Henri
Saraux, Alain
Trope, Sonia
Combe, Bernard
JOINT BONE SPINE, 2014, 81 (04) : 287 - 297
[9] 2012 Brazilian Society of Rheumatology Consensus on the management of comorbidities in patients with rheumatoid arthritis
Pereira, Ivanio Alves
Henrique da Mota, Licia Maria
Cruz, Boris Afonso
Brenol, Claiton Viegas
Rezende Fronza, Lucila Stange
Bertolo, Manoel Barros
Carioca de Freitas, Max Victor
da Silva, Nilzio Antonio
Louzada-Junior, Paulo
Neubarth Giorgi, Rina Dalva
Correa Lima, Rodrigo Aires
Castelar Pinheiro, Geraldo da Rocha
REVISTA BRASILEIRA DE REUMATOLOGIA, 2012, 52 (04) : 474 - 495
[10] 2024 update of the recommendations of the French Society of Rheumatology for the diagnosis and management of patients with rheumatoid arthritis
Fautrel, Bruno
Kedra, Joanna
Rempenault, Claire
Juge, Pierre-Antoine
Drouet, Juliette
Avouac, Jerome
Baillet, Athan
Brocq, Olivier
Alegria, Guillermo Carvajal
Constantin, Arnaud
Dernis, Emmanuelle
Gaujoux-Viala, Cecile
Goeb, Vincent
Gottenberg, Jacques-Eric
Le Goff, Benoit
Marotte, Hubert
Richez, Christophe
Salmon, Jean-Hugues
Saraux, Alain
Senbel, Eric
Seror, Raphaele
Tournadre, Anne
Vittecoq, Olivier
Escaffre, Pascale
Vacher, Danielle
Dieude, Philippe
Daien, Claire
JOINT BONE SPINE, 2024, 91 (06)

← 1 2 3 4 5 →