Development of a novel neodymium compound for in vivo fluorescence imaging

被引：14

作者：

Aita, Kazuki ^{[1
]}

Temma, Takashi ^{[1
]}

Kuge, Yuji ^{[1
]}

Saji, Hideo ^{[1
]}

机构：

[1] Kyoto Univ, Dept Pathofunct Bioanal, Grad Sch Pharmaceut Sci, Kyoto, Japan

来源：

LUMINESCENCE | 2007年 / 22卷 / 05期

关键词：

neodymium; near-infrared; fluorescein; energy transfer; long-lived luminescence;

D O I：

10.1002/bio.984

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

We developed a novel fluorescent probe that contains the neodymium(III) complex moiety and fluorescein moiety. This probe can emit long-lived near-infrared luminescence derived from a Nd ion through excitation of the fluorescein moiety with visible light (lambda(ex) = 488 nm, lambda(em) = 880 nm, lifetime = 2.3 mu s). These results indicate the possibility of the probe as a candidate for in vivo fluorescence molecular imaging. Copyright (C) 2007 John Wiley & Sons, Ltd.

引用

页码：455 / 461

页数：7

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