Current research activity in biosensors

被引：208

作者：

Nakamura, H ^{[1
]}

Karube, I ^{[1
]}

机构：

[1] Tokyo Univ Technol, Sch Bion, Tokyo 1920982, Japan

来源：

ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2003年 / 377卷 / 03期

关键词：

biosensor; molecular recognition element; array; environmental biosensor; food biosensor; clinical biosensor;

D O I：

10.1007/s00216-003-1947-5

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Biosensors consist of a molecular recognition element and a transducer. Since the first biosensor was developed by Updike and Hicks [1] many biosensors and their associated techniques have been studied and developed. In this review current research activity on the fundamentals and applications of biosensors is summarized. In discussion of the former, molecular recognition elements, techniques and tools for biosensor construction, and basic biosensor devices are introduced. Coverage of the latter includes description of biosensors for environmental, food, and clinical fields. Chemical sensors developed in our laboratory for environmental monitoring are also described. This review mainly summarizes work performed by our group and by our colleagues, and refers to the main review articles summarizing each field of biosensor research in recent years.

引用

页码：446 / 468

页数：23

共 412 条

[1] Effect of incident angle of light on sensitivity and detection limit for layers of antibody with surface plasmon resonance spectroscopy [J].