Phase 2 Results of APR-246 and Azacitidine (AZA) in Patients with TP53 mutant Myelodysplastic Syndromes (MDS) and Oligoblastic Acute Myeloid Leukemia (AML)

被引：43

作者：

Sallman, David A. ^{[1
]}

DeZern, Amy E. ^{[2
]}

Garcia-Manero, Guillermo ^{[3
]}

Steensma, David P. ^{[4
]}

Roboz, Gail J. ^{[5
,6
]}

Sekeres, Mikkael A. ^{[7
]}

Cluzeau, Thomas ^{[8
]}

Sweet, Kendra L. ^{[1
]}

McLemore, Amy F. ^{[1
]}

McGraw, Kathy ^{[1
]}

Puskas, John ^{[1
]}

Zhang, Ling ^{[9
]}

Yao, Jiqiang ^{[10
]}

Mo, Qianxing ^{[10
]}

Nardelli, Lisa ^{[1
]}

Al Ali, Najla ^{[1
]}

Padron, Eric ^{[1
]}

Korbel, Greg ^{[11
]}

Attar, Eyal C. ^{[11
]}

Kantarjian, Hagop M. ^{[3
]}

Lancet, Jeffrey E. ^{[1
]}

Fenaux, Pierre ^{[12
]}

List, Alan F. ^{[1
]}

Komrokji, Rami S. ^{[1
,13
]}

机构：

[1] H Lee Moffitt Canc Ctr & Res Inst, Dept Malignant Hematol, Tampa, FL USA

[2] Johns Hopkins Univ, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD USA

[3] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Houston, TX 77030 USA

[4] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02115 USA

[5] Weill Cornell Med, New York, NY USA

[6] New York Presbyterian Hosp, New York, NY USA

[7] Cleveland Clin, Leukemia Program, Dept Hematol & Med Oncol, Taussig Canc Inst, Cleveland, OH 44106 USA

[8] Univ Nice Sophia Antipolis, Cote DAzur Univ, Dept Hematol, CHU Nice, Nice, France

[9] H Lee Moffitt Canc Ctr & Res Inst, Dept Hematopathol & Lab Med, Tampa, FL USA

[10] H Lee Moffitt Canc Ctr & Res Inst, Dept Biostat & Bioinformat, Tampa, FL USA

[11] Aprea Therapeut, Boston, MA USA

[12] Paris 7 Univ, Hop St Louis, Paris, France

[13] H Lee Moffitt Canc Ctr & Res Inst, Div Malignant Hematol, Tampa, FL USA

来源：

BLOOD | 2019年 / 134卷

关键词：

D O I：

10.1182/blood-2019-131055

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

676

引用

页数：6