Diagnostic strategy and comparison of clinical scores for pulmonary embolism

被引:5
作者
Blondon, M. [1 ]
Le Gal, G. [2 ]
Righini, M. [3 ]
机构
[1] Hop Univ Geneve, Serv Med Interne Gen, CH-1211 Geneva 14, Switzerland
[2] CHU Brest, Serv Pneumol & Malad Resp, Hop Cavale Blanche, F-29609 Brest, France
[3] Hop Univ Geneve, Serv Angiol & Hemostase, CH-1211 Geneva 14, Switzerland
来源
REVUE DE MEDECINE INTERNE | 2010年 / 31卷 / 11期
关键词
Pulmonary embolism; Diagnostic strategy; Clinical score; D dimers; Computed tomographic scan; REVISED GENEVA SCORE; FACTOR-V-LEIDEN; VENOUS THROMBOEMBOLIC DISEASE; DEEP-VEIN THROMBOSIS; ACTIVATED PROTEIN-C; D-DIMER; COMPUTED-TOMOGRAPHY; PRETEST PROBABILITY; ANTICARDIOLIPIN ANTIBODIES; EMERGENCY-DEPARTMENT;
D O I
10.1016/j.revmed.2010.07.012
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The diagnostic approach to pulmonary embolism can be divided in several consecutive steps First of all the clinician must Identify the patients with potential pulmonary embolism based on clinical presentation and the presence or absence of personal risk factors Further Investigations can then be guided by the use of a clinical probability score The revised Geneva score and the Wells score are the most validated tools They are reliable in stratifying patients Into low intermediate and high-risk categories When clinical probability is low or intermediate the dosage of D-dimers is helpful A negative result excludes pulmonary embolism with a very high negative predictive value close to 100% When positive a multidetector thoracic CT will confirm or exclude the diagnosis The utility of a lower-limb venous ultrasound is very low and its use is therefore no longer recommended (C) 2010 Societe nationale francaise de medecine interne (SNFMI) Published by Elsevier Masson SAS All rights reserved
引用
收藏
页码:742 / 749
页数:8
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