Central Nervous System Tissue Regeneration after Intracerebral Hemorrhage: The Next Frontier

被引：26

作者：

Zhang, Ruiyi ^{[1
,2
,3
]}

Xue, Mengzhou ^{[3
]}

Yong, Voon Wee ^{[1
,2
]}

机构：

[1] Univ Calgary, Hotchkiss Brain Inst, Calgary, AB T3A 4X9, Canada

[2] Univ Calgary, Dept Clin Neurosci, Calgary, AB T3A 4X9, Canada

[3] Zhengzhou Univ, Affiliated Hosp 2, Zhengzhou 450014, Peoples R China

来源：

CELLS | 2021年 / 10卷 / 10期

基金：

中国国家自然科学基金;

关键词：

intracerebral hemorrhage; tissue regeneration; neurogenesis; remyelination; angiogenesis; neuroinflammation; drug therapy; stem cells; rehabilitation; biomaterial; MESENCHYMAL STEM-CELLS; PROMOTES FUNCTIONAL RECOVERY; HEALTH-CARE PROFESSIONALS; RANDOMIZED CONTROLLED-TRIAL; ADULT HUMAN BRAIN; RAT MODEL; MATRIX METALLOPROTEINASES; RECEPTOR; INFLAMMATORY MEDIATORS; NEUROLOGICAL FUNCTIONS;

D O I：

10.3390/cells10102513

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Despite marked advances in surgical techniques and understanding of secondary brain injury mechanisms, the prognosis of intracerebral hemorrhage (ICH) remains devastating. Harnessing and promoting the regenerative potential of the central nervous system may improve the outcomes of patients with hemorrhagic stroke, but approaches are still in their infancy. In this review, we discuss the regenerative phenomena occurring in animal models and human ICH, provide results related to cellular and molecular mechanisms of the repair process including by microglia, and review potential methods to promote tissue regeneration in ICH. We aim to stimulate research involving tissue restoration after ICH.</p>

引用

页数：22

共 50 条

[21] Central nervous system regeneration-where are we?
Williams, A.
QJM-AN INTERNATIONAL JOURNAL OF MEDICINE, 2014, 107 (05) : 335 - 339
[22] Nanotechnology approaches for the regeneration and neuroprotection of the central nervous system
Silva, GA
SURGICAL NEUROLOGY, 2005, 63 (04): : 301 - 306
[23] Olfactory receptors in neural regeneration in the central nervous system
Franco, Rafael
Garrigos, Claudia
Capo, Toni
Serrano-Marin, Joan
Rivas-Santisteban, Rafael
Lillo, Jaume
NEURAL REGENERATION RESEARCH, 2025, 20 (09) : 2480 - 2494
[24] Primary Central Nervous System Vasculitis Presenting With Intracranial Hemorrhage
Salvarani, Carlo
Brown, Robert D., Jr.
Calamia, Kenneth T.
Christianson, Teresa J. H.
Huston, John, III
Meschia, James F.
Giannini, Caterina
Miller, Dylan V.
Hunder, Gene G.
ARTHRITIS AND RHEUMATISM, 2011, 63 (11): : 3598 - 3606
[25] Adult hippocampal neurogenesis (AHN) controls central nervous system and promotes peripheral nervous system regeneration via physical exercise
Zalouli, Vahideh
Rajavand, Hosnieh
Bayat, Mahdi
Khaleghnia, Jalil
Sharifianjazi, Fariborz
Jafarinazhad, Farzad
Beheshtizadeh, Nima
BIOMEDICINE & PHARMACOTHERAPY, 2023, 165
[26] Bridging the gap of axonal regeneration in the central nervous system: A state of the art review on central axonal regeneration
Costa, Goncalo
Ribeiro, Filipa F. F.
Sebastiao, Ana M. M.
Muir, Elizabeth M. M.
Vaz, Sandra H. H.
FRONTIERS IN NEUROSCIENCE, 2022, 16
[27] Treatment of Intracerebral Hemorrhage with Tranexamic Acid After Thrombolysis with Tissue Plasminogen Activator
K. F. French
Jacob White
R. E. Hoesch
Neurocritical Care, 2012, 17 : 107 - 111
[28] Transcriptomic changes during regeneration of the central nervous system in an echinoderm
Mashanov, Vladimir S.
Zueva, Olga R.
Garcia-Arraras, Jose E.
BMC GENOMICS, 2014, 15
[29] Central nervous system regeneration in ascidians: cell migration and differentiation
de Abreu, Isadora Santos
Ribas Wajsenzon, Ines Julia
Dias Jr, Jose Correa
Allodi, Silvana
Monteiro-de-Barros, Cintia
CELL AND TISSUE RESEARCH, 2022, 390 (03) : 335 - 354
[30] Treatment of Intracerebral Hemorrhage with Tranexamic Acid After Thrombolysis with Tissue Plasminogen Activator
French, K. F.
White, Jacob
Hoesch, R. E.
NEUROCRITICAL CARE, 2012, 17 (01) : 107 - 111

← 1 2 3 4 5 →