Self-assembly of amphiphilic ABA random triblock copolymers in water

被引：7
|
作者：
Kozawa, Susan K. [1 ,2 ]
Matsumoto, Kazuma [1 ]
Suzuki, Ayaka [1 ]
Sawamoto, Mitsuo [1 ,3 ]
Terashima, Takaya [1 ]
机构：
[1] Kyoto Univ, Grad Sch Engn, Dept Polymer Chem, Nishikyo Ku, Kyoto 6158510, Japan
[2] Case Western Reserve Univ, Dept Macromol Sci & Engn, 2100 Adelbert Rd, Cleveland, OH 44106 USA
[3] Chubu Univ, Inst Sci & Technol Res, 1200 Matsumoto Cho, Kasugai, Aichi 4878501, Japan
来源：
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY | 2019年 / 57卷 / 03期
关键词：
amphiphilic random copolymer; block copolymer; micelle; self-assembly; thermoresponsive; DRUG-DELIVERY; POLYMERIC MICELLES; BLOCK-COPOLYMERS; SYSTEMS; TECHNOLOGIES;
D O I：
10.1002/pola.29178
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Self-assembly of amphiphilic ABA random triblock copolymers in water serves as a novel approach to create unique structure micelles connected with flexible linkages. The ABA triblock copolymers consist of amphiphilic random copolymers bearing hydrophilic poly(ethylene glycol) and hydrophobic dodecyl pendants as the A segments and a hydrophilic poly(ethylene oxide) (PEO) as the middle B segment. The A block is varied in dodecyl methacrylate content of 20%-50% and degree of polymerization (DP) of 100-200. By controlling the composition and DP of the A block, various architectures can be tailor-made as micelles in water: PEO-linked double core unimer micelles, PEO-looped unimer or dimer micelles, and multichain micelles. Those PEO-linked or looped micelles further exhibit thermoresponsive solubility in water. (c) 2018 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2019, 57, 313-321
引用
收藏
页码：313 / 321
页数：9
相关论文
共 50 条
  • [1] Self-assembly of ABA amphiphilic triblock copolymers into vesicles in dilute solution
    Zhu, JT
    Jiang, Y
    Liang, HJ
    Jiang, W
    JOURNAL OF PHYSICAL CHEMISTRY B, 2005, 109 (18): : 8619 - 8625
  • [2] Synthesis and self-assembly of cationic amphiphilic triblock copolymers
    Yang, Bingbing
    Shi, Yan
    Gaofenzi Cailiao Kexue Yu Gongcheng/Polymeric Materials Science and Engineering, 2014, 30 (10): : 38 - 42
  • [3] Self-assembly of ABA triblock copolymers under soft confinement
    Sheng, Yuping
    An, Jian
    Zhu, Yutian
    CHEMICAL PHYSICS, 2015, 452 : 46 - 52
  • [4] SYNTHESIS OF ABA TRIBLOCK IONIC COPOLYMERS AND THEIR SELF-ASSEMBLY IN SOLUTION
    Tang Xuezhi
    Pan Caiyuan
    ACTA POLYMERICA SINICA, 2008, (12): : 1192 - 1197
  • [5] Self-Assembly and Photoresponsivity Property of Amphiphilic ABA Triblock Copolymers Containing Azobenzene Moieties in Dilute Solution
    Tang, Xinde
    Gao, Longcheng
    Fan, Xinghe
    Liang, Xiaochao
    Zhou, Qifeng
    MACROMOLECULAR CHEMISTRY AND PHYSICS, 2009, 210 (18) : 1556 - 1562
  • [6] Self-assembly of metal–polymer analogues of amphiphilic triblock copolymers
    Zhihong Nie
    Daniele Fava
    Eugenia Kumacheva
    Shan Zou
    Gilbert C. Walker
    Michael Rubinstein
    Nature Materials, 2007, 6 : 609 - 614
  • [7] Self-assembly of mixed amphiphilic triblock copolymers in aqueous solution
    Liu, TB
    Nace, VM
    Chu, B
    LANGMUIR, 1999, 15 (09) : 3109 - 3117
  • [8] Self-healing yet selectively adhesive hydrogels by the self-assembly of amphiphilic random triblock copolymers
    Terashima, Takaya
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2019, 258
  • [9] Self-assembly of ABA triblock copolymers based on functionalized polydimethylsiloxane and polymethyloxazoline
    Theogarajan, Luke
    Li, Hangsheng
    Busse, Karsten
    Desai, Salil
    Kressler, Joerg
    Scholz, Carmen
    POLYMER INTERNATIONAL, 2010, 59 (09) : 1191 - 1198
  • [10] Unexpected Consequences of Block Polydispersity on the Self-Assembly of ABA Triblock Copolymers
    Widin, Joan M.
    Schmitt, Adam K.
    Schmitt, Andrew L.
    Im, Kyuhyun
    Mahanthappa, Mahesh K.
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (08) : 3834 - 3844
12345