Chemotaxis of Molecular Dyes in Polymer Gradients in Solution

被引：26

作者：

Guha, Rajarshi ^{[1
]}

Mohajerani, Farzad ^{[1
]}

Collins, Matthew ^{[2
]}

Ghosh, Subhadip ^{[2
]}

Sen, Ayusman ^{[2
]}

Velegol, Darrell ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem Engn, University Pk, PA 16802 USA

[2] Penn State Univ, Dept Chem, University Pk, PA 16802 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2017年 / 139卷 / 44期

基金：

美国国家科学基金会;

关键词：

CHEMICAL-POTENTIAL GRADIENTS; HYDROPHOBIC INTERACTION; ENZYME; MACROMOLECULES; NANOSCALE; COMPLEXES; DIFFUSION; TRANSPORT; PROTEINS; DESIGN;

D O I：

10.1021/jacs.7b08783

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chemotaxis provides a mechanism for directing the transport of molecules along chemical gradients. Here, we show the chemotactic migration of dye molecules in response to the gradients of several different neutral polymers. The magnitude of chemotactic response depends on the structure of the monomer, polymer molecular weight and concentration, and the nature of the solvent. The mechanism involves cross diffusion up the polymer gradient, driven by favorable dye polymer interaction. Modeling allows us to quantitatively evaluate the strength of the interaction and the effect of the various parameters that govern chemotaxis.

引用

页码：15588 / 15591

页数：4

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