Enantioselective hydrogenation of ketopantolactone: Effect of stereospecific product crystallization during reaction

被引：79

作者：

Schurch, M ^{[1
]}

Kunzle, N ^{[1
]}

Mallat, T ^{[1
]}

Baiker, A ^{[1
]}

机构：

[1] ETH Zentrum, Swiss Fed Inst Technol, Tech Chem Lab, CH-8092 Zurich, Switzerland

来源：

JOURNAL OF CATALYSIS | 1998年 / 176卷 / 02期

关键词：

enantioselective; hydrogenation; Pt/alumina; ketopantolactone; cinchonidine;

D O I：

10.1006/jcat.1998.2085

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The hydrogenation of ketopantolactone over cinchonidine-modified Pt/alumina has been reinvestigated, focussing on the misleading effect of stereospecific product crystallization during reaction at medium to high conversions. The appropriate choice of reaction conditions afforded 91.6 +/- 0.5% ee to R-(-)-pantolactone. (C) 1998 Academic Press.

引用

页码：569 / 571

页数：3

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