Methyl 5-(4-hydroxy-3-methoxyphenyl)-2-(4-methoxybenzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate

In the title compound, C(24)H(22)N(2)O(6)S, a pyrimidine ring substituted with 4-hydroxy-3-methoxyphenyl is fused with a thiazole ring. The 4-hydroxy-3-methoxyphenyl group is positioned axially to the pyrimidine ring, making a dihedral angle 85.36 (7)degrees. The pyrimidine ring adopts a twist boat conformation. In the crystal, O-H center dot center dot center dot N interactions result in a chain running along the b axis. The carbonyl O atom bonded to the thiazole ring is involved in two C-H center dot center dot center dot O hydrogen-bond interactions forming centrosymmetric dimers; the ten- and six-membered rings resulting from these interactions have R(2)(2)(10) and R(1)(2)(6) motifs, respectively.