(Pentamethylcyclopentadienyl)Iridium Dichloride Dimer {[IrCp*Cl2]2}: A Novel Efficient Catalyst for the Cycloisomerizations of Homopropargylic Diols and N-Tethered Enynes

被引：35

作者：

Benedetti, Erica ^{[1
,2
]}

Simonneau, Antoine ^{[1
]}

Hours, Alexandra ^{[1
]}

Amouri, Hani ^{[1
]}

Penoni, Andrea ^{[2
]}

Palmisano, Giovanni ^{[2
]}

Malacria, Max ^{[1
]}

Goddard, Jean-Philippe ^{[1
]}

Fensterbank, Louis ^{[1
]}

机构：

[1] UPMC Univ Paris 06, Inst Parisien Chim Mol, CNRS, IUMR 7201,FR 2769, F-75005 Paris, France

[2] Univ Insubria, Dipartimento Sci Chim & Ambientali, I-22100 Como, Italy

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2011年 / 353卷 / 11-12期

关键词：

bicyclic compounds; cycloisomerization; enynes; homogeneous catalysis; iridium(III); CATIONIC GOLD(I) COMPLEXES; TERMINAL ALKYNES; ATOM ECONOMY; OXIDATIVE CYCLIZATION; PLATINUM CATALYSIS; BICYCLIC KETALS; IDEAL SYNTHESIS; BOND FORMATION; ALCOHOLS; IRIDIUM;

D O I：

10.1002/adsc.201100124

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

(Pentamethylcyclopentadienyl)iridium dichloride dimer {[IrCp*Cl-2](2)}-catalyzed hydroalkoxylation of bis-homopropargylic alcohols provides an efficient access to dioxabicyclo[2.2.1]ketals. The cycloisomerizations proceed under mild conditions, with low catalytic loadings and short reaction times. This new protocol involving an Ir(III) catalyst also promoted the cycloisomerization of nitrogen-tethered 1,6-enynes to give azabicyclo[4.1.0]heptenes, enhancing the synthetic potential of our method.

引用

页码：1908 / 1912

页数：5

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