Successful treatment of a high-grade intraepithelial neoplasia with imiquimod, with vulvar pemphigus as a side effect

被引：32

作者：

Campagne, G ^{[1
]}

Roca, M ^{[1
]}

Martínez, A ^{[1
]}

机构：

[1] Dept Obstet & Gynaecol, Clin Bella Med, Altea 03590, Spain

来源：

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 2003年 / 109卷 / 02期

关键词：

vulva; intraepithelial neoplasia; drug-induced pemphigus; imiquimod;

D O I：

10.1016/S0301-2115(02)00482-7

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Imiquimod modulates the immune response, and is a new approach for treatment of papillomavirus-associated lesions, although it has not been approved for the treatment of intraepithelial neoplasia. We present a case of a patient treated with imiquimod on account of high-grade intraepithelial neoplasia in the vulva and other locations. The posterior biopsies confirm the absence of lesions but show drug-induced pemphigus as a side effect. (C) 2002 Published by Elsevier Science Ireland Ltd.

引用

页码：224 / 227

页数：4

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