Discrimination between moderate and severe disease may be used in patients with either treated or untreated allergic rhinitis

被引：30

作者：

Valero, A. ^{[13
]}

Ferrer, M. ^{[1
]}

Baro, E. ^{[2
]}

Sastre, J. ^{[3
]}

Navarro, A. M. ^{[4
]}

Marti-Guadano, E. ^{[5
]}

Davila, I. ^{[6
]}

del Cuvillo, A. ^{[7
]}

Colas, C. ^{[8
]}

Antepara, I. ^{[9
]}

Alonso, J. ^{[1
]}

Mola, O. ^{[10
]}

Izquierdo, I. ^{[10
]}

Mullol, J. ^{[11
,12
]}

机构：

[1] Inst Municipal Invest Med IMIM IMAS, Hlth Serv, Res Unit, Barcelona, Spain

[2] 3D Hlth Res, Barcelona, Spain

[3] Fdn Jimenez Diaz, Serv Alergia, E-28040 Madrid, Spain

[4] Hosp El Tomillar, Unidad Alergia, Seville, Spain

[5] Hosp St Pere Claver, Serv Allergia, Barcelona, Spain

[6] Hosp Clin Salamanca, Serv Alergia, Salamanca, Spain

[7] Clin Dr Lobaton, Cadiz, Spain

[8] Hosp Clin Lozano Blesa, Serv Alergia, Zaragoza, Spain

[9] Hosp Basurto, Serv Alergia, Bilbao, Spain

[10] Grp Uriach SA, Unidad Desarrollo Clin, Barcelona, Spain

[11] IDIBAPS, Unitat Rinol, Barcelona, Catalunya, Spain

[12] IDIBAPS, Clin Olfacte, Serv Otorinolaringol, Hosp Clin, Barcelona, Catalunya, Spain

[13] Hosp Clin Barcelona, Unitat Allergia, Serv Pneumol & Allergia Resp, Barcelona 08036, Spain

来源：

ALLERGY | 2010年 / 65卷 / 12期

关键词：

allergic rhinitis; ARIA; moderate; quality of life; severe; severity; QUALITY-OF-LIFE; PRIMARY-CARE; ARIA; 2008; IMPACT; CLASSIFICATION; UPDATE; QUESTIONNAIRE; COLLABORATION; INTERMITTENT; ESPRINT-15;

D O I：

10.1111/j.1398-9995.2010.02410.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Background: Allergic rhinitis (AR) is a common disease with major socioeconomic burden and a significant impact on quality of life. Objective: The aim of this study was to discriminate between moderate and severe AR patients whether receiving treatment or not, using a modified criterion of allergic rhinitis and its impact on asthma (ARIA) classification. Methods: The modified ARIA severity classification (J Allergy Clin Immunol, 120, 2007, 359) categorizes AR as mild (no items affected), moderate (1-3 items affected), and severe (all four items affected). We applied these criteria to 1666 treated and 1058 untreated AR patients and compared their symptoms total four-symptom score (T4SS) and quality of life (ESPRINT-15), according to their clinical severity. Results: Allergic rhinitis clinical status was significantly worse (P < 0.001) in treated than in untreated patients. For both treated and untreated patients, T4SS and ESPRINT-15 Quality of life scores were significantly worse (P < 0.001) in severe than in moderate patients. Conclusions: The modified ARIA severity classification is a useful clinical tool to discriminate moderate from severe AR among both treated and untreated patients.

引用

页码：1609 / 1613

页数：5

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