Intraoperative Radiotherapy of the Breast for Early-Stage Breast Cancer: Ready for Primetime

被引：4

作者：

Holmes, Dennis R. ^{[1
]}

机构：

[1] Los Angeles Ctr Womens Hlth, Los Angeles, CA 90015 USA

来源：

BREAST JOURNAL | 2015年 / 21卷 / 02期

关键词：

breast cancer; ELIOT; intraoperative radiotherapy; IORT; TARGIT; CONSENSUS STATEMENT; TRIAL; IRRADIATION; SOCIETY; RISK;

D O I：

10.1111/tbj.12375

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The findings of the TARGIT A and ELIOT prospective, randomized controlled trials provide compelling data regarding the efficacy and safety of single fraction intraoperative radiotherapy as an alternative to standard postoperative radiotherapy in the management of early-stage breast cancer. This editorial summarizes the findings of both studies and discusses the importance of patient selection in identifying potential candidates for intraoperative radiotherapy.

引用

页码：181 / 184

页数：4

共 11 条

[1] Patient preferences regarding intraoperative versus external beam radiotherapy following breast-conserving surgery [J].

Alvarado, Michael D. ;

Conolly, Jay ;

Park, Catherine ;

Sakata, Theadora ;

Mohan, Aron J. ;

Harrison, Brittany L. ;

Hayes, Mitchell ;

Esserman, Laura J. ;

Ozanne, Elissa M. .

BREAST CANCER RESEARCH AND TREATMENT, 2014, 143 (01) :135-140

[2]

American Society of Breast Surgeons (ASBS), 2011, AM SOC BREAST SURG C

[3]

Clarke M, 2005, LANCET, V336, P106

[4] Patient selection for accelerated partial-breast irradiation (APBI) after breast-conserving surgery: Recommendations of the Groupe Europeen de Curietherapie-European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) breast cancer working group based on clinical evidence (2009) [J].

Csaba Polgar ;

Van Limbergen, Erik ;

Poetter, Richard ;

Kovacs, Gyoergy ;

Polo, Alfredo ;

Lyczek, Jaroslaw ;

Hildebrandt, Guido ;

Niehoff, Peter ;

Luis Guinot, Jose ;

Guedea, Ferran ;

Johansson, Bengt ;

Ott, Oliver J. ;

Major, Tibor ;

Strnad, Vratislav .

RADIOTHERAPY AND ONCOLOGY, 2010, 94 (03) :264-273

[5] Risk of Ischemic Heart Disease in Women after Radiotherapy for Breast Cancer [J].

Darby, Sarah C. ;

Ewertz, Marianne ;

McGale, Paul ;

Bennet, Anna M. ;

Blom-Goldman, Ulla ;

Bronnum, Dorthe ;

Correa, Candace ;

Cutter, David ;

Gagliardi, Giovanna ;

Gigante, Bruna ;

Jensen, Maj-Britt ;

Nisbet, Andrew ;

Peto, Richard ;

Rahimi, Kazem ;

Taylor, Carolyn ;

Hall, Per .

NEW ENGLAND JOURNAL OF MEDICINE, 2013, 368 (11) :987-998

[6] Mammographic Findings after Intraoperative Radiotherapy of the Breast [J].

Rivera, Ronald ;

Smith-Bronstein, Virginia ;

Villegas-Mendez, Sylvia ;

Rayhanabad, Jessica ;

Sheth, Pulin ;

Rashtian, Afshin ;

Holmes, Dennis R. .

RADIOLOGY RESEARCH AND PRACTICE, 2012, 2012

[7] The American Brachytherapy Society consensus statement for accelerated partial breast irradiation [J].

Shah, Chirag ;

Vicini, Frank ;

Wazer, David E. ;

Arthur, Douglas ;

Patel, Rakesh R. .

BRACHYTHERAPY, 2013, 12 (04) :267-277

[8] ACCELERATED PARTIAL BREAST IRRADIATION CONSENSUS STATEMENT FROM THE AMERICAN SOCIETY FOR RADIATION ONCOLOGY (ASTRO) [J].

Smith, Benjamin D. ;

Arthur, Douglas W. ;

Buchholz, Thomas A. ;

Haffty, Bruce G. ;

Hahn, Carol A. ;

Hardenbergh, Patricia H. ;

Julian, Thomas B. ;

Marks, Lawrence B. ;

Todor, Dorin A. ;

Vicini, Frank A. ;

Whelan, Timothy J. ;

White, Julia ;

Wo, Jennifer Y. ;

Harris, Jay R. .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2009, 74 (04) :987-1001

[9] Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial [J].

Vaidya, Jayant S. ;

Wenz, Frederik ;

Bulsara, Max ;

Tobias, Jeffrey S. ;

Joseph, David J. ;

Keshtgar, Mohammed ;

Flyger, Henrik L. ;

Massarut, Samuele ;

Alvarado, Michael ;

Saunders, Christobel ;

Eiermann, Wolfgang ;

Metaxas, Marinos ;

Sperk, Elena ;

Suetterlin, Marc ;

Brown, Douglas ;

Esserman, Laura ;

Roncadin, Mario ;

Thompson, Alastair ;

Dewar, John A. ;

Holtveg, Helle M. R. ;

Pigorsch, Steffi ;

Falzon, Mary ;

Harris, Eleanor ;

Matthews, April ;

Brew-Graves, Chris ;

Potyka, Ingrid ;

Corica, Tammy ;

Williams, Norman R. ;

Baum, Michael .

LANCET, 2014, 383 (9917) :603-613

[10] Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial [J].