Colorectal cancer: cetuximab, KRAS, BRAF, PIK3CA mutations and beyond

被引：0

作者：

Katsios, Christos ^{[1
]}

Ziogas, Dimosthenis E. ^{[1
]}

Roukos, Dimitrios H. ^{[1
]}

机构：

[1] Univ Ioannina, Sch Med, Dept Surg, GR-45110 Ioannina, TK, Greece

来源：

EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY | 2010年 / 4卷 / 05期

关键词：

BRAF; cancer genome; cetuximab; chemotherapy; colorectal cancer; genetic and environment interactions; KRAS; survival; GENOTYPE-PHENOTYPE MAP; PERSONALIZED MEDICINE; MOLECULAR NETWORKS; HUMAN BREAST; CHEMOTHERAPY; TRASTUZUMAB; BEVACIZUMAB; CHALLENGES; LANDSCAPES; THERAPY;

D O I：

10.1586/EGH.10.62

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

引用

页码：525 / 529

页数：5

共 40 条

[1] THE SEQUENCE EXPLOSION [J].

不详 .

NATURE, 2010, 464 (7289) :670-670

[2] The human genome at ten [J].

不详 .

NATURE, 2010, 464 (7289) :649-650

[3] SYSTEMS BIOLOGY When it is time to die [J].

Bastiaens, Philippe .

NATURE, 2009, 459 (7245) :334-335

[4] The landscape of somatic copy-number alteration across human cancers [J].

Beroukhim, Rameen ;

Mermel, Craig H. ;

Porter, Dale ;

Wei, Guo ;

Raychaudhuri, Soumya ;

Donovan, Jerry ;

Barretina, Jordi ;

Boehm, Jesse S. ;

Dobson, Jennifer ;

Urashima, Mitsuyoshi ;

Mc Henry, Kevin T. ;

Pinchback, Reid M. ;

Ligon, Azra H. ;

Cho, Yoon-Jae ;

Haery, Leila ;

Greulich, Heidi ;

Reich, Michael ;

Winckler, Wendy ;

Lawrence, Michael S. ;

Weir, Barbara A. ;

Tanaka, Kumiko E. ;

Chiang, Derek Y. ;

Bass, Adam J. ;

Loo, Alice ;

Hoffman, Carter ;

Prensner, John ;

Liefeld, Ted ;

Gao, Qing ;

Yecies, Derek ;

Signoretti, Sabina ;

Maher, Elizabeth ;

Kaye, Frederic J. ;

Sasaki, Hidefumi ;

Tepper, Joel E. ;

Fletcher, Jonathan A. ;

Tabernero, Josep ;

Baselga, Jose ;

Tsao, Ming-Sound ;

Demichelis, Francesca ;

Rubin, Mark A. ;

Janne, Pasi A. ;

Daly, Mark J. ;

Nucera, Carmelo ;

Levine, Ross L. ;

Ebert, Benjamin L. ;

Gabriel, Stacey ;

Rustgi, Anil K. ;

Antonescu, Cristina R. ;

Ladanyi, Marc ;

Letai, Anthony .

NATURE, 2010, 463 (7283) :899-905

[5] Fluorouracil, Leucovorin, and Oxaliplatin With and Without Cetuximab in the First-Line Treatment of Metastatic Colorectal Cancer [J].

Bokemeyer, Carsten ;

Bondarenko, Igor ;

Makhson, Anatoly ;

Hartmann, Joerg T. ;

Aparicio, Jorge ;

de Braud, Filippo ;

Donea, Serban ;

Ludwig, Heinz ;

Schuch, Gunter ;

Stroh, Christopher ;

Loos, Anja H. ;

Zubel, Angela ;

Koralewski, Piotr .

JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (05) :663-671

[6] LIFE IS COMPLICATED [J].

Hayden, Erika Check .

NATURE, 2010, 464 (7289) :664-667

[7] Has the revolution arrived? [J].

Collins, Francis .

NATURE, 2010, 464 (7289) :674-675

[8] Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis [J].

De Roock, Wendy ;

Claes, Bart ;

Bernasconi, David ;

De Schutter, Jef ;

Biesmans, Bart ;

Fountzilas, George ;

Kalogeras, Konstantine T. ;

Kotoula, Vassiliki ;

Papamichael, Demetris ;

Laurent-Puig, Pierre ;

Penault-Llorca, Frederique ;

Rougier, Philippe ;

Vincenzi, Bruno ;

Santini, Daniele ;

Tonini, Giuseppe ;

Cappuzzo, Federico ;

Frattini, Milo ;

Molinari, Francesca ;

Saletti, Piercarlo ;

De Dosso, Sara ;

Martini, Miriam ;

Bardelli, Alberto ;

Siena, Salvatore ;

Sartore-Bianchi, Andrea ;

Tabernero, Josep ;

Macarulla, Teresa ;

Di Fiore, Frederic ;

Gangloff, Alice Oden ;

Ciardiello, Fortunato ;

Pfeiffer, Per ;

Qvortrup, Camilla ;

Hansen, Tine Plato ;

Van Cutsem, Eric ;

Piessevaux, Hubert ;

Lambrechts, Diether ;

Delorenzi, Mauro ;

Tejpar, Sabine .

LANCET ONCOLOGY, 2010, 11 (08) :753-762

[9] Modelling the molecular circuitry of cancer [J].

Hahn, WC ;

Weinberg, RA .

NATURE REVIEWS CANCER, 2002, 2 (05) :331-341

[10] The hallmarks of cancer [J].

Hanahan, D ;

Weinberg, RA .

CELL, 2000, 100 (01) :57-70

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