2-[(E)-4-(Dimethylamino)benzylidene]indan-1-one

被引：3

作者：

Ali, Mohamed Ashraf ^{[2
]}

Ismail, Rusli ^{[2
]}

Choon, Tan Soo ^{[2
]}

Loh, Wan-Sin ^{[1
]}

Fun, Hoong-Kun ^{[1
]}

机构：

[1] Univ Sains Malaysia, Sch Phys, Xray Crystallog Unit, Usm 11800, Penang, Malaysia

[2] Univ Sains Malaysia, Inst Res Mol Med, Usm 11800, Penang, Malaysia

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2011年 / 67卷

关键词：

BIOLOGICAL EVALUATION; CHALCONES; AGENTS; DERIVATIVES;

D O I：

10.1107/S160053681102664X

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

In the title compound, C18H17NO, the dihydroindene ring system is approximately planar, with a maximum deviation of 0.041 (2) angstrom. This ring system is almost coplanar with the benzene ring, making a dihedral angle of 5.22 (9)degrees. In the crystal, intermolecular C-H center dot center dot center dot O hydrogen bonds link the molecules into chains along the b axis.

引用

页码：O1983 / U2508

页数：11

共 13 条

[1] (E)-2-[4-(Piperidin-1-yl)benzylidene]-2,3-dihydro-1H-inden-1-one [J].

Ali, Mohamed Ashraf ;

Ismail, Rusli ;

Choon, Tan Soo ;

Rosli, Mohd Mustaqim ;

Fun, Hoong-Kun .

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 :O2878-U734

[2]

[Anonymous], 2009, APEX2 SAINT SADABS

[3] Synthesis and biological evaluation of chalcones and their derived pyrazoles as potential cytotoxic agents [J].

Bhat, BA ;

Dhar, KL ;

Puri, SC ;

Saxena, AK ;

Shanmugavel, M ;

Qazi, GN .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (12) :3177-3180

[4] Synthesis and cytotoxic, anti-inflammatory, and anti-oxidant activities of 2′,5′-dialkoxylchalcones as cancer chemopreventive agents [J].

Cheng, Jen-Hao ;

Hung, Chi-Feng ;

Yang, Shyh-Chyun ;

Wang, Jih-Pyang ;

Won, Shen-Jeu ;

Lin, Chun-Nan .

BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 16 (15) :7270-7276

[5] Protein-linked DNA strand breaks induced by NSC 314622, a novel noncamptothecin topoisomerase I poison [J].

Kohlhagen, G ;

Paull, KD ;

Cushman, M ;

Nagafuji, P ;

Pommier, Y .

MOLECULAR PHARMACOLOGY, 1998, 54 (01) :50-58

[6] Structure-activity relationships of antileishmanial and antimalarial chalcones [J].

Liu, M ;

Wilairat, P ;

Croft, SL ;

Tan, ALC ;

Go, ML .

BIOORGANIC & MEDICINAL CHEMISTRY, 2003, 11 (13) :2729-2738

[7]

Prasad Y. R., 2006, INT J CHEM SCI, V4, P905

[8] A short history of SHELX [J].

Sheldrick, George M. .

ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2008, 64 :112-122

[9] Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents [J].

Solankee, Anjani ;

Kapadia, Kishor ;

Ciric, Ana ;

Sokovic, Marina ;

Doytchinova, Irini ;

Geronikaki, Athina .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2010, 45 (02) :510-518

[10] Structure validation in chemical crystallography [J].

Spek, Anthony L. .

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2009, 65 :148-155

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