Impact of tea drinking upon tuberculosis: a neglected issue

被引:18
作者
Chen, Mengshi [1 ,2 ]
Deng, Jing [1 ]
Li, Wufei [3 ]
Lin, Dan [1 ]
Su, Congxu [4 ]
Wang, Mian [1 ]
Li, Xun [1 ]
Abuaku, Benjamin Kwaku [1 ,5 ]
Tan, Hongzhuan [1 ]
Wen, Shi Wu [1 ,6 ,7 ]
机构
[1] Cent South Univ, Sch Publ Hlth, Dept Epidemiol & Hlth Stat, Changsha 410008, Hunan, Peoples R China
[2] Hunan Childrens Hosp, Changsha 410007, Hunan, Peoples R China
[3] Shaoyang Med Coll, Dept Nursing, Shaoyang 422000, Hunan, Peoples R China
[4] Yueyanglou Ctr Dis Control & Prevent, Yueyang 414000, Hunan, Peoples R China
[5] Univ Ghana, Coll Hlth Sci, Noguchi Mem Inst Med Res, Dept Epidemiol, Legon, Accra, Ghana
[6] Univ Ottawa, Dept Obstet & Gynaecol, Ottawa Hosp, Ottawa, ON, Canada
[7] Univ Ottawa, Dept Epidemiol & Community Med, Ottawa Hosp, Ottawa, ON, Canada
关键词
Tuberculosis; tea; ENOYL-ACP REDUCTASE; NF-KAPPA-B; GREEN TEA; EPIGALLOCATECHIN GALLATE; BIOMASS FUEL; POLYPHENOL; INHIBITION; DISEASE; OBESITY; RATS;
D O I
10.1186/s12889-015-1855-6
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Background: Tuberculosis (TB) is a global public health issue posing serious harm to the human health. Many studies have suggested that smoking and excessive alcohol consumption are risk factors for TB. Laboratory evidence suggests that EGCG in tea leaves can arrest the growth of tubercle bacillus. Can drinking tea lead to decreased susceptibility of TB in humans? Methods: A total of 574 TB patients and 582 healthy controls were recruited to participate in this case-control study. Self-designed questionnaire was used to collect data. Unconditioned logistic regression analysis was conducted to identify the associations between tea drinking and TB. Results: Tea drinking has a negative association with TB, with OR = 0.583(0.423, 0.804) and P < 0.05. Drinking black tea, oolong and green tea are all negative association with TB, with OR being 0.683(0.517, 0.902), 0.674(0.508, 0.894) and 0.534(0.349, 0.817) respectively and P < 0.05. Trend chi(2) test indicated a decreasing risk for TB with increased tea consumption, with P < 0.05. Conclusion: There is a significance negative association between tea drinking and TB. Promoting the consumption of tea as the daily drink among populations, particularly those with high TB risk, may reduce the incidence of TB in the populations.
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页数:5
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