Grayanane diterpenoids from the flowers of Rhododendron molle with cytotoxic activity against a Spodoptera frugiperda cell line

被引：46

作者：

Zhong, GH

Hu, MY ^{[1
]}

Wei, XY

Weng, QF

Xie, JJ

Liu, JX

Wang, WX

机构：

[1] S China Agr Univ, Lab Insect Toxicol, Guangzhou 510642, Peoples R China

[2] Minist Educ Peoples Republ China, Key Lab Pesticides & Chem Biol, Guangzhou 510642, Peoples R China

[3] Chinese Acad Sci, S China Inst Bot, Guangzhou 510650, Peoples R China

来源：

JOURNAL OF NATURAL PRODUCTS | 2005年 / 68卷 / 06期

关键词：

D O I：

10.1021/np049645t

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new grayanane diterpenoids, rhodomolins A (1) and B (2), together with two known diterpenoids, rhodomolleins I and rhodojaponin 111, were isolated from the flowers of Rhododendron molle. The structures of 1 and 2 were elucidated on the basis of interpretation of spectroscopic data. All compounds were evaluated for cytotoxic activity against the Spodoptera frugiperda cell line Sf-9 and gave IC50 values in the range 12-80 mu g/mL.

引用

页码：924 / 926

页数：3

共 22 条

[1]

CHEN CY, 1992, ACTA CHIM SINICA, V50, P237

[2]

Chen JS, 1987, CHINESE POISONOUS PL

[3] Diterpenoids from the flowers of Rhododendron molle [J].

Chen, SN ;

Zhang, HP ;

Wang, LQ ;

Bao, GH ;

Qin, GW .

JOURNAL OF NATURAL PRODUCTS, 2004, 67 (11) :1903-1906

[4]

Hu Mei-ying, 2000, Entomologia Sinica, V7, P65

[5] RESPONSE OF 5 INSECT SPECIES TO A BOTANICAL INSECTICIDE, RHODOJAPONIN-III [J].

HU, MY ;

KLOCKE, JA ;

CHIU, SF ;

KUBO, I .

JOURNAL OF ECONOMIC ENTOMOLOGY, 1993, 86 (03) :706-711

[6] GRAYANOID DITERPENE INSECT ANTIFEEDANTS AND INSECTICIDES FROM RHODODENDRON-MOLLE [J].

KLOCKE, JA ;

HU, MY ;

CHIU, SF ;

KUBO, I .

PHYTOCHEMISTRY, 1991, 30 (06) :1797-1800

[7]

Li CJ, 2003, ACTA CHIM SINICA, V61, P1153

[8] Diterpenoids from the fruits of Rhododendron molle [J].

Li, CJ ;

Wang, LQ ;

Chen, SN ;

Qin, GW .

JOURNAL OF NATURAL PRODUCTS, 2000, 63 (09) :1214-1217

[9]

Li XiaoDong, 1995, Journal of South China Agricultural University, V16, P80

[10]

LIU Z G, 1990, Yaoxue Xuebao, V25, P830

← 1 2 3 →