A synthetic approach towards the aromatic macrocyclic core of diazonamide A based on sp2-sp2 coupling protocols

被引：48

作者：

Boto, A ^{[1
]}

Ling, M ^{[1
]}

Meek, G ^{[1
]}

Pattenden, G ^{[1
]}

机构：

[1] Univ Nottingham, Dept Chem, Nottingham NG7 2RD, England

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 44期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/S0040-4039(98)01819-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The scope for a range of sp(2)-sp(2) coupling protocols to elaborate the phenyl-indole, indole-oxazole, oxazole-oxazole, and quaternary carbon units in the marine natural product diazonamide A 1 are described, leading to the synthesis of the benzofuran oxazoles 11a and 18, the benzofuran/biphenyl/indole 16, and the indole-bis-oxazole 25. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：8167 / 8170

页数：4

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