Decision making in the ageing brain: changes in affective and motivational circuits

被引:231
作者
Samanez-Larkin, Gregory R. [1 ]
Knutson, Brian [2 ]
机构
[1] Yale Univ, Dept Psychol, New Haven, CT 06520 USA
[2] Stanford Univ, Dept Psychol, Stanford, CA 94305 USA
关键词
AGE-RELATED DIFFERENCES; REWARD PREDICTION ERRORS; WHITE-MATTER INTEGRITY; PREFRONTAL CORTEX; ORBITOFRONTAL CORTEX; OLDER-ADULTS; NEURAL REPRESENTATIONS; COGNITIVE NEUROSCIENCE; INTERTEMPORAL CHOICE; FINANCIAL DECISIONS;
D O I
10.1038/nrn3917
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
As the global population ages, older decision makers will be required to take greater responsibility for their own physical, psychological and financial well-being. With this in mind, researchers have begun to examine the effects of ageing on decision making and associated neural circuits. A new 'affect-integration-motivation' (AIM) framework may help to clarify how affective and motivational circuits support decision making. Recent research has shed light on whether and how ageing influences these circuits, providing an interdisciplinary account of how ageing can alter decision making.
引用
收藏
页码:278 / 289
页数:12
相关论文
共 146 条
[41]   Learning to avoid in older age [J].
Frank, Michael J. ;
Kong, Lauren .
PSYCHOLOGY AND AGING, 2008, 23 (02) :392-398
[42]   Time discounting and time preference: A critical review [J].
Frederick, S ;
Loewenstein, G ;
O'Donoghue, T .
JOURNAL OF ECONOMIC LITERATURE, 2002, 40 (02) :351-401
[43]   Moment-to-moment brain signal variability: A next frontier in human brain mapping? [J].
Garrett, Douglas D. ;
Samanez-Larkin, Gregory R. ;
MacDonald, Stuart W. S. ;
Lindenberger, Ulman ;
McIntosh, Anthony R. ;
Grady, Cheryl L. .
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 2013, 37 (04) :610-624
[44]   Moment-to-moment signal variability in the human brain can inform models of stochastic facilitation now [J].
Garrett, Douglas D. ;
McIntosh, Anthony R. ;
Grady, Cheryl L. .
NATURE REVIEWS NEUROSCIENCE, 2011, 12 (10) :612-612
[45]   Blood Oxygen Level-Dependent Signal Variability Is More than Just Noise [J].
Garrett, Douglas D. ;
Kovacevic, Natasa ;
McIntosh, Anthony R. ;
Grady, Cheryl L. .
JOURNAL OF NEUROSCIENCE, 2010, 30 (14) :4914-4921
[46]   Risk, reward, and decision-making in a rodent model of cognitive aging [J].
Gilbert, Ryan J. ;
Mitchell, Marci R. ;
Simon, Nicholas W. ;
Banuelos, Cristina ;
Setlow, Barry ;
Bizon, Jennifer L. .
FRONTIERS IN NEUROSCIENCE, 2012, 6
[47]   BRAIN AGEING The cognitive neuroscience of ageing [J].
Grady, Cheryl .
NATURE REVIEWS NEUROSCIENCE, 2012, 13 (07) :491-505
[48]   Plasticity of the aging brain: New directions in cognitive neuroscience [J].
Gutchess, Angela .
SCIENCE, 2014, 346 (6209) :579-582
[49]   The Reward Circuit: Linking Primate Anatomy and Human Imaging [J].
Haber, Suzanne N. ;
Knutson, Brian .
NEUROPSYCHOPHARMACOLOGY, 2010, 35 (01) :4-26
[50]   Life Span Differences in Electrophysiological Correlates of Monitoring Gains and Losses during Probabilistic Reinforcement Learning [J].
Haemmerer, Dorothea ;
Li, Shu-Chen ;
Mueller, Viktor ;
Lindenberger, Ulman .
JOURNAL OF COGNITIVE NEUROSCIENCE, 2011, 23 (03) :579-592