A ratiometric two-photon fluorescent probe for fluoride ion imaging in living cells and zebrafish

被引：40
作者：
Hu, Wei [1 ]
Zeng, Lingyu [2 ]
Wang, Yanying [1 ]
Liu, Zhihong [2 ]
Ye, Xiaoxue [1 ]
Li, Chunya [1 ]
机构：
[1] South Cent Univ Nationalities, Coll Chem & Mat Sci, Key Lab Analyt Chem, State Ethn Affairs Commiss, Wuhan 430074, Peoples R China
[2] Wuhan Univ, Key Lab Analyt Chem Biol & Med, Minist Educ, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China
来源：
ANALYST | 2016年 / 141卷 / 18期
基金：
中国国家自然科学基金;
关键词：
BIOIMAGING APPLICATIONS; WATER; CHEMOSENSORS; MITOCHONDRIA; RECOGNITION; SENSOR;
D O I：
10.1039/c6an00905k
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Using 6-hydroxyl-quinoline-2-benzothiazole (HQB) as a two-photon fluorophore and tert-butyldiphenylsilyl as a recognition domain for F-, a ratiometric two-photon fluorescent fluoride probe, QF, was synthesized and fully characterized. QF displays both one-and two-photon ratiometric responses towards fluoride ions in aqueous solution. QF was enabled to detect exogenous fluoride ions in living cells by a ratiometric method. Two-photon microscopic imaging of fluoride ions in living HeLa cells and zebrafish has also been achieved. QF has been demonstrated to be an excellent fluorescent probe with high selectivity, low cytotoxicity and good photostability.
引用
收藏
页码：5450 / 5455
页数：6
相关论文
共 38 条
  • [1] Tuning of the optical properties and Lewis acidity of dibenzopnictogenaborins by modification on bridging main group elements
    Agou, Tomohiro
    Kobayashi, Junji
    Kawashima, Takayuki
    [J]. INORGANIC CHEMISTRY, 2006, 45 (22) : 9137 - 9144
  • [2] Aminobenzohydrazide based colorimetric and 'turn-on' fluorescence chemosensor for selective recognition of fluoride
    Anand, Thangaraj
    Sivaramana, Gandhi
    Iniya, Murugan
    Siva, Ayyanar
    Chellappa, Duraisamy
    [J]. ANALYTICA CHIMICA ACTA, 2015, 876 : 1 - 8
  • [3] Fluorescent Chemosensors Based on Spiroring-Opening of Xanthenes and Related Derivatives
    Chen, Xiaoqiang
    Pradhan, Tuhin
    Wang, Fang
    Kim, Jong Seung
    Yoon, Juyoung
    [J]. CHEMICAL REVIEWS, 2012, 112 (03) : 1910 - 1956
  • [4] Energy transfer cassettes based on organic fluorophores: construction and applications in ratiometric sensing
    Fan, Jiangli
    Hu, Mingming
    Zhan, Peng
    Peng, Xiaojun
    [J]. CHEMICAL SOCIETY REVIEWS, 2013, 42 (01) : 29 - 43
  • [5] Freshney R., 2005, CULTURE ANIMAL CELLS, P490
  • [6] A new pyrene based highly sensitive fluorescence probe for copper(II) and fluoride with living cell application
    Goswami, Shyamaprosad
    Chakraborty, Shampa
    Paul, Sima
    Halder, Sandipan
    Panja, Sukanya
    Mukhopadhyay, Subhra Kanti
    [J]. ORGANIC & BIOMOLECULAR CHEMISTRY, 2014, 12 (19) : 3037 - 3044
  • [7] ESTABLISHMENT OF A NORADRENERGIC CLONAL LINE OF RAT ADRENAL PHEOCHROMOCYTOMA CELLS WHICH RESPOND TO NERVE GROWTH-FACTOR
    GREENE, LA
    TISCHLER, AS
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (07) : 2424 - 2428
  • [8] A Rapid Aqueous Fluoride Ion Sensor with Dual Output Modes
    Hu, Rui
    Feng, Jiao
    Hu, Dehui
    Wang, Shuangqing
    Li, Shayu
    Li, Yi
    Yang, Guoqiang
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (29) : 4915 - 4918
  • [9] Recent progress in luminescent and colorimetric chemosensors for detection of thiols
    Jung, Hyo Sung
    Chen, Xiaoqiang
    Kim, Jong Seung
    Yoon, Juyoung
    [J]. CHEMICAL SOCIETY REVIEWS, 2013, 42 (14) : 6019 - 6031
  • [10] Highly Selective "Turn-On" Fluorescent and Colorimetric Sensing of Fluoride Ion Using 2-(2-Hydroxyphenyl)-2,3-dihydroquinolin-1H)-one based on Excited-State Proton Transfer
    Kanagaraj, Kuppusamy
    Pitchumani, Kasi
    [J]. CHEMISTRY-AN ASIAN JOURNAL, 2014, 9 (01) : 146 - 152
1234