Signaling and host cell invasion by Trypanosoma cruzi

被引：86
|
作者：
Burleigh, BA [1 ]
Andrews, NW [1 ]
机构：
[1] Yale Univ, Sch Med, Dept Cell Biol, New Haven, CT 06520 USA
来源：
CURRENT OPINION IN MICROBIOLOGY | 1998年 / 1卷 / 04期
关键词：
D O I：
10.1016/S1369-5274(98)80066-0
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Signal transduction events triggered in mammalian host cells by the obligate intracellular parasite Trypanosoma cruzi are required for invasion. Infective T. cruzi trypomastigotes elicit Ca2+ signaling in mammalian host cells and activate transforming growth factor-P receptor signaling pathways. The elevation of Ca2+ in T. cruzi, induced by host-cell contact, is also required for invasion, extending the concept of host-pathogen 'cross-talk' to invasive protozoan pathogens.
引用
收藏
页码：461 / 465
页数：5
相关论文
共 50 条
  • [1] Mechanisms of Host Cell Invasion by Trypanosoma cruzi
    Caradonna, Kacey L.
    Burleigh, Barbara A.
    ADVANCES IN PARASITOLOGY, VOL 76: CHAGAS DISEASE, PT B, 2011, 76 : 33 - 61
  • [2] Cell signaling during Trypanosoma cruzi invasion
    Maeda, Fernando Y.
    Cortez, Cristian
    Yoshida, Nobuko
    FRONTIERS IN IMMUNOLOGY, 2012, 3
  • [3] Host cell invasion by Trypanosoma cruzi:: Akt II
    Burleigh, B
    Woolsey, A
    Sunwoo, L
    Brachmann, S
    Cantley, L
    MOLECULAR BIOLOGY OF THE CELL, 2001, 12 : 139A - 139A
  • [4] Molecular mechanisms of host cell invasion by Trypanosoma cruzi
    Epting, Conrad L.
    Coates, Bria M.
    Engman, David M.
    EXPERIMENTAL PARASITOLOGY, 2010, 126 (03) : 283 - 291
  • [5] Oligopeptidase B-dependent signaling mediates host cell invasion by Trypanosoma cruzi
    Caler, EV
    de Avalos, SV
    Haynes, PA
    Andrews, NW
    Burleigh, BA
    EMBO JOURNAL, 1998, 17 (17): : 4975 - 4986
  • [6] Pentachloropseudilin Treatment Impairs Host Cell Invasion by Trypanosoma cruzi
    da Costa, Mylla Spirandelli
    Borges, Bruna Cristina
    Marques, Isabella Teixeira
    de Oliveira, Rayane Cristina
    Teixeira, Thaise Lara
    Santos, Julia de Gouveia
    da Silva, Claudio Vieira
    CHEMBIOCHEM, 2022, 23 (18)
  • [7] Host cell invasion by Trypanosoma cruzi: a unique strategy that promotes persistence
    Fernandes, Maria Cecilia
    Andrews, Norma W.
    FEMS MICROBIOLOGY REVIEWS, 2012, 36 (03) : 734 - 747
  • [8] The Trypanosoma cruzi-host-cell interplay:: location, invasion, retention
    Andrade, LO
    Andrews, NW
    NATURE REVIEWS MICROBIOLOGY, 2005, 3 (10) : 819 - 823
  • [9] Features of host cell invasion by different infective forms of Trypanosoma cruzi
    Mortara, RA
    Procópio, DO
    Barros, HC
    Verbisck, NV
    Andreoli, WK
    Silva, RBS
    da Silva, S
    MEMORIAS DO INSTITUTO OSWALDO CRUZ, 1999, 94 : 135 - 137
  • [10] The Trypanosoma cruzi–host-cell interplay: location, invasion, retention
    Luciana O. Andrade
    Norma W. Andrews
    Nature Reviews Microbiology, 2005, 3 : 819 - 823
12345