Trastuzumab emtansine in the systemic treatment of HER-2-positive breast cancer brain metastases

被引:1
作者
Frenel, Jean-Sebastien [1 ]
Bally, Olivia [2 ]
Bourbouloux, Emmanuelle [1 ]
Berton-Rigaud, Dominique [1 ]
Campone, Mario [1 ]
Bachelot, Thomas [2 ]
Heudel, Pierre-Etienne [2 ]
机构
[1] Inst Cancerol Ouest, Dept Med Oncol, F-44800 St Herblain, France
[2] Ctr Leon Berard, Dept Med Oncol, F-69008 Lyon, France
关键词
Brain metastases; Breast cancer; Anti-HER2 systemic treatment; LAPATINIB PLUS CAPECITABINE; SURGICAL RESECTION; RADIOTHERAPY; T-DM1;
D O I
10.1016/j.bulcan.2016.02.005
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:507 / 510
页数:4
相关论文
共 15 条
[1]   Lapatinib plus capecitabine in patients with previously untreated brain metastases from HER2-positive metastatic breast cancer (LANDSCAPE): a single-group phase 2 study [J].
Bachelot, Thomas ;
Romieu, Gilles ;
Campone, Mario ;
Dieras, Veronique ;
Cropet, Claire ;
Dalenc, Florence ;
Jimenez, Marta ;
Le Rhun, Emilie ;
Pierga, Jean-Yves ;
Goncalves, Anthony ;
Leheurteur, Marianne ;
Domont, Julien ;
Gutierrez, Maya ;
Cure, Herve ;
Ferrero, Jean-Marc ;
Labbe-Devilliers, Catherine .
LANCET ONCOLOGY, 2013, 14 (01) :64-71
[2]   Breast cancer brain metastases responding to primary systemic therapy with T-DM1 [J].
Bartsch, Rupert ;
Berghoff, Anna S. ;
Preusser, Matthias .
JOURNAL OF NEURO-ONCOLOGY, 2014, 116 (01) :205-206
[3]   Central Nervous System Metastases in Patients with HER2-Positive Metastatic Breast Cancer: Incidence, Treatment, and Survival in Patients from registHER [J].
Brufsky, Adam M. ;
Mayer, Musa ;
Rugo, Hope S. ;
Kaufman, Peter A. ;
Tan-Chiu, Elizabeth ;
Tripathy, Debu ;
Tudor, Iulia Cristina ;
Wang, Lisa I. ;
Brammer, Melissa G. ;
Shing, Mona ;
Yood, Marianne Ulcickas ;
Yardley, Denise A. .
CLINICAL CANCER RESEARCH, 2011, 17 (14) :4834-4843
[4]   Selective Permeabilization of the BloodBrain Barrier at Sites of Metastasis [J].
Connell, John J. ;
Chatain, Grgoire ;
Cornelissen, Bart ;
Vallis, Katherine A. ;
Hamilton, Alastair ;
Seymour, Len ;
Anthony, Daniel C. ;
Sibson, Nicola R. .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2013, 105 (21) :1634-1643
[5]   Trastuzumab emtansine (Kadcyla®) approval in HER2-positive metastatic breast cancers [J].
Guerin, Mathilde ;
Sabatier, Renaud ;
Goncalves, Anthony .
BULLETIN DU CANCER, 2015, 102 (04) :390-397
[6]   Population-based outcomes after brain radiotherapy in patients with brain metastases from breast cancer in the Pre-Trastuzumab and Trastuzumab eras [J].
Karam, Irene ;
Hamilton, Sarah ;
Nichol, Alan ;
Woods, Ryan ;
Speers, Caroline ;
Kennecke, Hagen ;
Tyldesley, Scott .
RADIATION ONCOLOGY, 2013, 8
[7]   Adjuvant Whole-Brain Radiotherapy Versus Observation After Radiosurgery or Surgical Resection of One to Three Cerebral Metastases: Results of the EORTC 22952-26001 Study [J].
Kocher, Martin ;
Soffietti, Riccardo ;
Abacioglu, Ufuk ;
Villa, Salvador ;
Fauchon, Francois ;
Baumert, Brigitta G. ;
Fariselli, Laura ;
Tzuk-Shina, Tzahala ;
Kortmann, Rolf-Dieter ;
Carrie, Christian ;
Ben Hassel, Mohamed ;
Kouri, Mauri ;
Valeinis, Egils ;
van den Berge, Dirk ;
Collette, Sandra ;
Collette, Laurence ;
Mueller, Rolf-Peter .
JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (02) :134-141
[8]   Trastuzumab emtansine (T-DM1) versus lapatinib plus capecitabine in patients with HER2-positive metastatic breast cancer and central nervous system metastases: a retrospective, exploratory analysis in EMILIA [J].
Krop, I. E. ;
Lin, N. U. ;
Blackwell, K. ;
Guardino, E. ;
Huober, J. ;
Lu, M. ;
Miles, D. ;
Samant, M. ;
Welslau, M. ;
Dieras, V. .
ANNALS OF ONCOLOGY, 2015, 26 (01) :113-119
[9]   Trastuzumab emtansine versus treatment of physician's choice for pretreated HER2-positive advanced breast cancer (TH3RESA): a randomised, open-label, phase 3 trial [J].
Krop, Ian E. ;
Kim, Sung-Bae ;
Gonzalez-Martin, Antonio ;
LoRusso, Patricia M. ;
Ferrero, Jean-Marc ;
Smitt, Melanie ;
Yu, Ron ;
Leung, Abraham C. F. ;
Wildiers, Hans .
LANCET ONCOLOGY, 2014, 15 (07) :689-699
[10]  
Michel LL, 2015, ANTICANCER RES, V35, P5085