Composite tissue allotransplantation

被引:10
作者
Tai, C [1 ]
Goldenberg, M [1 ]
Schuster, KM [1 ]
Kann, BR [1 ]
Hewitt, CW [1 ]
机构
[1] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Div Surg Res, Camden, NJ 08103 USA
关键词
composite tissue allotransplantation; graft-vs-host disease; hand transplant; tolerance; vascularized bone marrow;
D O I
10.1080/08941930390215006
中图分类号
R61 [外科手术学];
学科分类号
摘要
Composite tissue allotransplantation (CTA) recently took its first steps in the clinical arena in 1998 with the successful hand transplant performed in Lyons, France. That single operation represented a culmination of many years of laboratory research in multiple fields involving integumentary/musculoskeletal transplantation. Here we review the prerequisite developments in the field of immunology, microsurgery, and pharmacotherapy that helped bring CTA to clinical reality. This new field still has many unanswered questions which are addressed below. Additionally, new evolving research in CTA is also discussed.
引用
收藏
页码:193 / 201
页数:9
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