Application of gold nanoparticles to X-ray diagnostics and photothermal therapy of cancer

被引：0

作者：

Terentyuk, G. S. ^{[1
]}

Maksimova, I. L. ^{[2
]}

Tuchin, V. V. ^{[2
]}

Zharov, V. P. ^{[3
]}

Khlebtsov, B. N. ^{[4
]}

Bogatyrev, V. A. ^{[4
]}

Dykman, L. A. ^{[4
]}

Khlebtsov, N. G. ^{[4
]}

机构：

[1] First Vet Clin, Saratov, Russia

[2] Saratov NG Chernyshevskii State Univ, Dept Opt & Biomed Phys, Saratov, Russia

[3] Univ Arkansas Med Sci, Philips Class Laser Labs, Little Rock, AR 72205 USA

[4] RAS, Inst Biochem & Physiol Plants & Microorganisms, Saratov, Russia

来源：

SARATOV FALL MEETING 2006: COHERENT OPTICS OF ORDERED AND RANDOM MEDIA VII | 2007年 / 6536卷

关键词：

gold nanoparticles; cancer; contrast agents; laser photothermolysis;

D O I：

10.1117/12.753446

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We describe applications of colloidal gold nanoparticles and silica/gold nanoshells to photothermal therapy and Xray diagnostics of cancer exemplified by spontaneous tumor of cats and dog. It is shown that the contrast of X-ray images of a cat mammalian tumor can be increased significantly by injection of 3-5-nm gold nanoparticles. We also present preliminary results of a complex approach to treatment a dog mouth cavity melanoma by using immunotherapy together with laser photothermolysis enhanced with silica/gold nanoshells.

引用

页数：12

共 39 条

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