Iridium complex nanoparticle mediated radiopharmaceutical-excited phosphorescence imaging

被引:8
作者
Hou, Yutong [1 ,2 ]
Wang, Chenchen [1 ,2 ]
Chen, Ming [1 ,2 ]
Wang, Mingwei [3 ]
Deng, Guang [1 ,2 ]
Yang, Hong [1 ,2 ]
Zhou, Zhiguo [1 ,2 ]
Yang, Shiping [1 ,2 ]
机构
[1] Shanghai Normal Univ, Key Lab Resource Chem, Educ Minist, Shanghai 200234, Peoples R China
[2] Shanghai Normal Univ, Shanghai Key Lab Rare Earth Funct Mat, Shanghai 200234, Peoples R China
[3] Fudan Univ, Shanghai Med Coll, Dept Nucl Med, 270 DongAn Rd, Shanghai 200032, Peoples R China
基金
中国国家自然科学基金;
关键词
IN-VIVO; PHOTODYNAMIC THERAPY; QUANTUM-DOT; LUMINESCENCE;
D O I
10.1039/c9cc07399j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We firstly perpared liposome coated [Ir(pq)(2)(bpy)]Cl (Ir@liposome) as a transducer for radiopharmaceutical (F-18-FDG) excited phosphorescence imaging (REPI). Ir@liposome-based REPI exhibited deep tissue penetration and high signal-to-noise ratio in the tumor.
引用
收藏
页码:14442 / 14445
页数:4
相关论文
共 26 条
  • [1] Boschi F., 2014, CURR MOL IMAG, V3, P106, DOI DOI 10.2174/2211555203666141128002406
  • [2] Optical imaging as an expansion of nuclear medicine: Cerenkov-based luminescence vs fluorescence-based luminescence
    Chin, Patrick T. K.
    Welling, Mick M.
    Meskers, Stefan C. J.
    Olmos, Renato A. Valdes
    Tanke, Hans
    van Leeuwen, Fijs W. B.
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2013, 40 (08) : 1283 - 1291
  • [3] Cherenkov Radiation-Mediated In Situ Excitation of Discrete Luminescent Lanthanide Complexes
    Cosby, Alexia G.
    Ahn, Shin Hye
    Boros, Eszter
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 57 (47) : 15496 - 15499
  • [4] Theranostic Liposomes with HypoxiaActivated Prodrug to Effectively Destruct Hypoxic Tumors Post-Photodynamic Therapy
    Feng, Liangzhu
    Cheng, Liang
    Dong, Ziliang
    Tao, Danlei
    Barnhart, Todd E.
    Cai, Weibo
    Chen, Meiwan
    Liu, Zhuang
    [J]. ACS NANO, 2017, 11 (01) : 927 - 937
  • [5] Enhanced Cerenkov luminescence tomography analysis based on Y2O3:Eu3+ rare earth oxide nanoparticles
    Gao, Yongheng
    Ma, Xiaowei
    Kang, Fei
    Yang, Weidong
    Liu, Yi
    Wang, Zhengjie
    Ma, Wenhui
    Wang, Zhe
    Li, Guoquan
    Cao, Xu
    Wang, Jing
    [J]. BIOMEDICAL OPTICS EXPRESS, 2018, 9 (12): : 6091 - 6102
  • [6] Weight Multispectral Reconstruction Strategy for Enhanced Reconstruction Accuracy and Stability With Cerenkov Luminescence Tomography
    Guo, Hongbo
    He, Xiaowei
    Liu, Muhan
    Zhang, Zeyu
    Hu, Zhenhua
    Tian, Jie
    [J]. IEEE TRANSACTIONS ON MEDICAL IMAGING, 2017, 36 (06) : 1337 - 1346
  • [7] Efficiency phosphorescent OLEDs with a low roll-off based on a hetero-triplet iridium complex
    Han, Liangliang
    Zhang, Dongyu
    Wang, Jun
    Lan, Zhenggang
    Yang, Renqiang
    [J]. DYES AND PIGMENTS, 2015, 113 : 649 - 654
  • [8] Theranostic Iridium(III) Complexes as One- and Two-Photon Phosphorescent Trackers to Monitor Autophagic Lysosomes
    He, Liang
    Tan, Cai-Ping
    Ye, Rui-Rong
    Zhao, Yi-Zhi
    Liu, Ya-Hong
    Zhao, Qiang
    Ji, Liang-Nian
    Mao, Zong-Wan
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 53 (45) : 12137 - 12141
  • [9] A multifunctional iridium-carbazolyl orange phosphor for high-performance two-element WOLED exploiting Exciton-Managed fluorescence/phosphorescence
    Ho, Cheuk-Lam
    Wong, Wai-Yeung
    Wang, Qi
    Ma, Dongge
    Wang, Lixiang
    Lin, Zhenyang
    [J]. ADVANCED FUNCTIONAL MATERIALS, 2008, 18 (06) : 928 - 937
  • [10] Nanoparticle-mediated radiopharmaceutical-excited fluorescence molecular imaging allows precise image-guided tumor-removal surgery
    Hu, Zhenhua
    Chi, Chongwei
    Liu, Muhan
    Guo, Hongbo
    Zhang, Zeyu
    Zeng, Chaoting
    Ye, Jinzuo
    Wang, Jing
    Tian, Jie
    Yang, Weidong
    Xu, Wanhai
    [J]. NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2017, 13 (04) : 1323 - 1331