The question of Plasmodium faliciparum population structure

被引:29
作者
Awadalla, P [1 ]
Walliker, D
Babiker, H
Mackinnon, M
机构
[1] Univ Calif Davis, Ctr Populat Biol, Davis, CA 95616 USA
[2] Univ Calif Davis, Sect Evolut & Ecol, Davis, CA 95616 USA
[3] Univ Edinburgh, Inst Cell Anim & Populat Biol, Edinburgh EH9 3JT, Midlothian, Scotland
关键词
D O I
10.1016/S1471-4922(01)02034-7
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Understanding how genetic variation in malaria parasites is structured across populations has benefits for researchers interested in finding loci that affect the ability of the parasite to resist host immunity or drugs. In a recent paper, Tim Anderson and colleagues have provided a broad-scale analysis of Plasmodium falciparum population structure. Their results provide an indication of the feasibility of using population-genetic and genetic-mapping approaches to pinpoint selected loci, in addition to reconciling some previously disparate views of population structure in malaria.
引用
收藏
页码:351 / 353
页数:3
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