Factors associated with Leishmania infantum infection in dogs from urban areas endemic for visceral leishmaniasis in Brazil

被引:4
作者
Barbosa, David Soeiro [1 ]
Belo, Vinicius Silva [2 ]
Bezerra, Juliana Maria Trindade [3 ]
Figueiredo, Fabiano Borges [4 ]
Werneck, Guilherme Loureiro [5 ,6 ]
机构
[1] Univ Fed Minas Gerais, Inst Biol Sci, Dept Parasitol, Av Presidente Antonio Carlos 6627, BR-31270901 Belo Horizonte, MG, Brazil
[2] Univ Fed Sao Joao del Rei, Campus Ctr Oeste Dona Lindu,Rua Sebastiao Goncalve, BR-35501296 Divinopolis, MG, Brazil
[3] State Univ Maranhao Campus Lago Pedra UEMA, Biol Sci Degree Course, Ave R Sarney S-N, BR-65715000 Lago Da Pedra, MA, Brazil
[4] Oswaldo Cruz Fdn ICC Fiocruz, Carlos Chagas Inst, Cell Biol Lab, Rua Prof Algacyr Munhoz Mader 3775, BR-81350010 Curitiba, Paana, Brazil
[5] Univ Fed Rio de Janeiro, Inst Studies Publ Hlth, Ave Horacio Macedo S-N, BR-21941598 Rio De Janeiro, RJ, Brazil
[6] Univ Estado Rio De Janeiro, Social Med Inst, Dept Epidemiol, Rua Sao Francisco Xavier 524, BR-20550013 Rio De Janeiro, RJ, Brazil
关键词
Brazil; Dogs; Risk factors; Visceral leishmaniasis; CANINE LEISHMANIASIS; DIAGNOSIS; EPIDEMIOLOGY; POPULATION; STATE;
D O I
10.1016/j.rvsc.2022.09.035
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
There are gaps in the knowledge of the factors associated with canine visceral leishmaniasis (CVL). Moreover, there is a need for studies conducted with appropriate sample selection and with standardized diagnostic methods, to assess the current infection status of animals. This study analyzed factors associated with Leishmania infantum infection in dogs from urban areas endemic for CVL in Brazil. Data from four cities in different regions of the country (Fortaleza, Brasilia, Palmas, and Bauru) were included, encompassing a large and heterogeneous sample group. Dogs were considered infected if they had positive results in parasitological tests (skin lesion culture, histological or immunohistochemical analysis of skin). Data analysis consisted of logistic regression with adjustment for the effect of cities as cluster variables, using generalized estimating equations. The canine positivity for L. infantum was 9.8%. Bauru had the highest percentage (18.7%), followed by Brasilia (8.4%), Fortaleza (7.9%), and Palmas (4%). Male animals were twice as likely to be infected as females (Confidence Interval (CI): 1.5-2.8). Dogs living outdoors were 1.5 times more likely to be positive (CI: 1.4-1.6). Dogs living in households rearing chickens were 40% less likely to be infected (CI: 0.5-0.8). A significant multiplicative interaction indicated that a protective association between purebred and CVL was stronger among dogs older than seven years. These findings provide evidence for the role of individual and environmental factors on L. infantum infection in dogs from endemic urban areas. They may be used for identifying groups of animals at higher risk for delivering control interventions.
引用
收藏
页码:651 / 656
页数:6
相关论文
共 35 条
[1]   Role of the domestic chicken (Gallus gallus) in the epidemiology of urban visceral leishmaniasis in Brazil [J].
Alexander, B ;
de Carvalho, RL ;
McCallum, H ;
Pereira, MH .
EMERGING INFECTIOUS DISEASES, 2002, 8 (12) :1480-1485
[2]   Responsible companion animal guardianship is associated with canine visceral leishmaniasis: an analytical cross-sectional survey in an urban area of southeastern Brazil [J].
Araujo Soares, Paulo Henrique ;
da Silva, Eduardo Sergio ;
Penaforte, Klauber Menezes ;
Nascimento Ribeiro, Renata Aparecida ;
Gama de Melo, Marcella Oliveira ;
Cardoso, Diogo Tavares ;
Santos, Ingrid Morselli ;
Machado, Raissa Cotta ;
Carneiro Trindade, Clara Lemos ;
Rodrigues Cunha, Anna Karolyna ;
Teixeira-Neto, Rafael Goncalves ;
de Melo, Saulo Nascimento ;
de Aquino, Vanessa Vilela ;
Belo, Vinicius Silva .
BMC VETERINARY RESEARCH, 2022, 18 (01)
[3]   Reliability of techniques used in the diagnosis of canine visceral leishmaniasis by the national control program in Brazil: A survey in an area of recent transmission [J].
Belo, Vinicius Silva ;
Gregorio, Eliana Aparecida ;
Teixeira-Neto, Rafael Goncalves ;
Mariano da Rocha Lima, Ana Cristina Vianna ;
Sampaio Pereira, Agnes Antonia ;
Marcelino, Andreza Pain ;
Paz, Gustavo Fontes ;
da Silva, Eduardo Sergio .
PREVENTIVE VETERINARY MEDICINE, 2017, 146 :10-15
[4]   A systematic review and meta-analysis of the factors associated with Leishmania infantum infection in dogs in Brazil [J].
Belo, Vinicius Silva ;
Struchiner, Claudio Jose ;
Werneck, Guilherme Loureiro ;
Barbosa, David Soeiro ;
de Oliveira, Robson Bruniera ;
Teixeira Neto, Rafael Goncalves ;
da Silva, Eduardo Sergio .
VETERINARY PARASITOLOGY, 2013, 195 (1-2) :1-13
[5]   Synthetic Sex Pheromone in a Long-Lasting Lure Attracts the Visceral Leishmaniasis Vector, Lutzomyia longipalpis, for up to 12 Weeks in Brazil [J].
Bray, Daniel P. ;
Carter, Vicky ;
Alves, Graziella B. ;
Brazil, Reginaldo P. ;
Bandi, Krishna K. ;
Hamilton, James G. C. .
PLOS NEGLECTED TROPICAL DISEASES, 2014, 8 (03)
[6]   Prevalence and Factors Associated with Leishmania infantum Infection of Dogs from an Urban Area of Brazil as Identified by Molecular Methods [J].
Coura-Vital, Wendel ;
Marques, Marcos Jose ;
Veloso, Vanja Maria ;
Roatt, Bruno Mendes ;
de Oliveira Aguiar-Soares, Rodrigo Dian ;
Soares Reis, Levi Eduardo ;
Braga, Samuel Leoncio ;
Franco Morais, Maria Helena ;
Reis, Alexandre Barbosa ;
Carneiro, Mariangela .
PLOS NEGLECTED TROPICAL DISEASES, 2011, 5 (08)
[7]  
da Saude Ministerio, 2014, MAN VIG CONTR LEISHM
[8]   Canine visceral leishmaniasis evaluation in Poxoreo, Mato Grosso State, Brazil [J].
De Azevedo, Marcia Avila A. ;
Dias, Ana Karinak K. ;
De Paula, Henrique B. ;
Perri, Silvia Helena V. ;
Nunes, Caris M. .
REVISTA BRASILEIRA DE PARASITOLOGIA VETERINARIA, 2008, 17 (03) :123-127
[9]   Risk mapping of visceral leishmaniasis in Brazil [J].
de Azevedo, Thiago Salomao ;
Lorenz, Camila ;
Chiaravalloti-Neto, Francisco .
REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL, 2019, 52
[10]   Genetic structure of allopatric populations of Lutzomyia longipalpis sensu lato in Brazil [J].
de Sousa-Paula, Lucas Christian ;
da Silva, Lidiane Gomes ;
da Silva Junior, Wilson Jose ;
Santiago Figueiredo Junior, Carlos Alberto ;
Nery Costa, Carlos Henrique ;
Costa Pessoa, Felipe Arley ;
Dantas-Torres, Filipe .
ACTA TROPICA, 2021, 222