Synergies between synthetic biology and metabolic engineering

被引:98
作者
Nielsen, Jens [1 ]
Keasling, Jay D. [2 ,3 ,4 ]
机构
[1] Chalmers, Dept Chem & Biol Engn, S-41296 Gothenburg, Sweden
[2] Joint Bioenergy Inst, Emeryville, CA USA
[3] Univ Calif Berkeley, Dept Chem & Biomol Engn, Dept Bioengn, Berkeley, CA 94720 USA
[4] Univ Calif Berkeley, Lawrence Berkeley Lab, Phys Biosci Div, Berkeley, CA 94720 USA
关键词
GENOME;
D O I
10.1038/nbt.1937
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
引用
收藏
页码:693 / 695
页数:3
相关论文
共 6 条
[1]   The growing scope of applications of genome-scale metabolic reconstructions using Escherichia coli [J].
Feist, Adam M. ;
Palsson, Bernhard O. .
NATURE BIOTECHNOLOGY, 2008, 26 (06) :659-667
[2]   Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome [J].
Gibson, Daniel G. ;
Glass, John I. ;
Lartigue, Carole ;
Noskov, Vladimir N. ;
Chuang, Ray-Yuan ;
Algire, Mikkel A. ;
Benders, Gwynedd A. ;
Montague, Michael G. ;
Ma, Li ;
Moodie, Monzia M. ;
Merryman, Chuck ;
Vashee, Sanjay ;
Krishnakumar, Radha ;
Assad-Garcia, Nacyra ;
Andrews-Pfannkoch, Cynthia ;
Denisova, Evgeniya A. ;
Young, Lei ;
Qi, Zhi-Qing ;
Segall-Shapiro, Thomas H. ;
Calvey, Christopher H. ;
Parmar, Prashanth P. ;
Hutchison, Clyde A., III ;
Smith, Hamilton O. ;
Venter, J. Craig .
SCIENCE, 2010, 329 (5987) :52-56
[3]   A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology [J].
Herrgard, Markus J. ;
Swainston, Neil ;
Dobson, Paul ;
Dunn, Warwick B. ;
Arga, K. Yalcin ;
Arvas, Mikko ;
Bluethgen, Nils ;
Borger, Simon ;
Costenoble, Roeland ;
Heinemann, Matthias ;
Hucka, Michael ;
Le Novere, Nicolas ;
Li, Peter ;
Liebermeister, Wolfram ;
Mo, Monica L. ;
Oliveira, Ana Paula ;
Petranovic, Dina ;
Pettifer, Stephen ;
Simeonidis, Evangelos ;
Smallbone, Kieran ;
Spasic, Irena ;
Weichart, Dieter ;
Brent, Roger ;
Broomhead, David S. ;
Westerhoff, Hans V. ;
Kirdar, Betuel ;
Penttila, Merja ;
Klipp, Edda ;
Palsson, Bernhard O. ;
Sauer, Uwe ;
Oliver, Stephen G. ;
Mendes, Pedro ;
Nielsen, Jens ;
Kell, Douglas B. .
NATURE BIOTECHNOLOGY, 2008, 26 (10) :1155-1160
[4]   Engineering Static and Dynamic Control of Synthetic Pathways [J].
Holtz, William J. ;
Keasling, Jay D. .
CELL, 2010, 140 (01) :19-23
[5]   It is all about metabolic fluxes [J].
Nielsen, J .
JOURNAL OF BACTERIOLOGY, 2003, 185 (24) :7031-7035
[6]   Metabolic engineering of β-lactam production [J].
Thykaer, J ;
Nielsen, J .
METABOLIC ENGINEERING, 2003, 5 (01) :56-69