Voriconazole serum concentrations in an infant treated for Trichosporon beigelii infection

被引：18
作者：
Maples, HD
Stowe, CD
Saccente, SL
Jacobs, RF
机构：
[1] Univ Arkansas Med Sci, Coll Pharm, Dept Pediat, Little Rock, AR 72205 USA
[2] Arkansas Childrens Hosp, Little Rock, AR 72202 USA
来源：
PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2003年 / 22卷 / 11期
关键词：
voriconazole; skin infection; Trichosporon beigelii; infant;
D O I：
10.1097/01.inf.0000095167.38306.76
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
A neutropenic 10-week-old with hemophagocytic lymphohistiocytosis developed a cutaneous Trichosporon beigelii infection that was treated for 78 days with voriconazole. A starting dose of 6 mg/kg/ dose every 12 h was initiated, and serum concentrations were obtained. The infection resolved; however, the serum concentrations obtained while receiving and not receiving phenobarbital would be considered subtherapeutic for the treatment of invasive fungal infection.
引用
收藏
页码：1022 / 1024
页数：3
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