EAACI consensus statement for investigation of work-related asthma in non-specialized centres

被引:63
|
作者
Moscato, G. [1 ]
Pala, G. [1 ]
Barnig, C. [2 ]
De Blay, F. [2 ]
Del Giacco, S. R. [3 ]
Folletti, I. [4 ]
Heffler, E. [5 ]
Maestrelli, P. [6 ]
Pauli, G. [2 ]
Perfetti, L. [1 ]
Quirce, S. [7 ,8 ]
Sastre, J. [9 ,10 ]
Siracusa, A. [11 ]
Walusiak-Skorupa, J. [12 ]
van Wjik, R. Gerth [13 ]
机构
[1] Fdn Salvatore Maugeri, Serv Allergol & Immunol Clin, IRCCS, Allergy & Immunol Unit,Inst Care & Res,Sci Inst P, I-27100 Pavia, Italy
[2] Univ Hosp Strasbourg, Div Asthma & Allergy, Dept Chest Dis, Strasbourg, France
[3] Univ Cagliari, Dept Med Sci M Aresu, Cagliari, Italy
[4] Univ Perugia, Dept Clin & Expt Med, Occupat Allergy Unit, Terni Hosp, I-06100 Perugia, Italy
[5] Univ Turin, ASO Mauriziano Umberto 1, Turin, Italy
[6] Univ Padua, Dept Environm Med & Publ Hlth, Padua, Italy
[7] Hosp La Paz IdiPAZ, Dept Allergy, Madrid, Spain
[8] CIBER Enfermedades Resp CIBERES, Madrid, Spain
[9] Fdn Jimenez Diaz, CIBER Enfermedades Resp, Ciberes, E-28040 Madrid, Spain
[10] Fdn Jimenez Diaz, Dept Allergy, E-28040 Madrid, Spain
[11] Univ Perugia, Dept Clin Expt Med, I-06100 Perugia, Italy
[12] Nofer Inst Occupat Med, Dept Occupat Dis, Lodz, Poland
[13] Erasmus MC, Sect Allergol, Dept Internal Med, Rotterdam, Netherlands
关键词
irritant-induced asthma; occupational asthma; specific inhalation challenge; work-exacerbated asthma; work-related asthma; EXHALED NITRIC-OXIDE; DIAGNOSING OCCUPATIONAL ASTHMA; DYSFUNCTION SYNDROME RADS; NONSPECIFIC BRONCHIAL HYPERRESPONSIVENESS; SPUTUM CELL COUNTS; AIRWAY INFLAMMATION; EOSINOPHILIC BRONCHITIS; EXPOSURE-RESPONSE; EARLY MARKER; CHALLENGE;
D O I
10.1111/j.1398-9995.2011.02784.x
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Work-related asthma (WRA) is a relevant problem in several countries, is cause of disability and socioeconomic consequences for both the patient and the society and is probably still underdiagnosed. A correct diagnosis is extremely important to reduce or limit the consequences of the disease. This consensus document was prepared by a EAACI Task Force consisting of an expert panel of allergologists, pneumologists and occupational physicians from different European countries. This document is not intended to address in detail the full diagnostic work-up of WRA, nor to be a formal evidence-based guideline. It is written to provide an operative protocol to allergologists and physicians dealing with asthma useful for identifying the subjects suspected of having WRA to address them to in-depth investigations in a specialized centre. No evidence-based system could be used because of the low grade of evidence of published studies in this area, and instead, key messages or suggestions are provided based on consensus of the expert panel members.
引用
收藏
页码:491 / 501
页数:11
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