An Allosteric Switch Primes Sequence-Specific DNA Recognition

被引：4
|
作者：
Walker, Matthew J. [1 ]
Varani, Gabriele [1 ]
机构：
[1] Univ Washington, Dept Chem, Seattle, WA 98195 USA
来源：
CELL | 2019年 / 176卷 / 1-2期
关键词：
PRIMASE;
D O I：
10.1016/j.cell.2018.12.020
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Regulation of protein-DNA binding specificity occurs through myriad mechanisms. Boudet et al. discover yet a new form of specificity through allosteric regulation, an ATP-induced structural switch that mediates specific DNA recognition in an archaeoeukaryotic primase.
引用
收藏
页码：4 / 6
页数：4
相关论文
共 50 条
  • [1] Sequence-specific recognition of DNA nanostructures
    Rusling, David A.
    Fox, Keith R.
    METHODS, 2014, 67 (02) : 123 - 133
  • [2] Sequence-specific DNA recognition by polyamides
    Dervan, PB
    Bürli, RW
    CURRENT OPINION IN CHEMICAL BIOLOGY, 1999, 3 (06) : 688 - 693
  • [3] Sequence-Specific DNA Recognition with Designed Peptides
    Boga, Sonia
    Bouzada, David
    Garcia Pena, Diego
    Vazquez Lopez, Miguel
    Eugenio Vazquez, M.
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2018, 2018 (03) : 249 - 261
  • [4] Coupling Sequence-specific Recognition to DNA Modification
    Estabrook, R. August
    Nguyen, Trung T.
    Fera, Nickolas
    Reich, Norbert O.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (34) : 22690 - 22696
  • [5] MECHANISM OF SEQUENCE-SPECIFIC DNA RECOGNITION ELUCIDATED
    BAUM, RM
    CHEMICAL & ENGINEERING NEWS, 1988, 66 (01) : 20 - &
  • [6] SEQUENCE-SPECIFIC DNA RECOGNITION BY THE SMAI ENDONUCLEASE
    WITHERS, BE
    DUNBAR, JC
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (12) : 6496 - 6504
  • [7] SEQUENCE-SPECIFIC DNA RECOGNITION AND CLEAVAGE BY METALLOBLEOMYCINS
    SUGIURA, Y
    RECUEIL DES TRAVAUX CHIMIQUES DES PAYS-BAS-JOURNAL OF THE ROYAL NETHERLANDS CHEMICAL SOCIETY, 1987, 106 (6-7): : 168 - 168
  • [8] DNA DETERMINANTS IN SEQUENCE-SPECIFIC RECOGNITION BY XMAL ENDONUCLEASE
    WITHERS, BE
    DUNBAR, JC
    NUCLEIC ACIDS RESEARCH, 1995, 23 (17) : 3571 - 3577
  • [9] Recognition properties of a sequence-specific DNA binding antibody
    LeBlanc, JF
    McLane, KE
    Parren, PWHI
    Burton, DR
    Ghazal, P
    BIOCHEMISTRY, 1998, 37 (17) : 6015 - 6022
  • [10] Modulation of DNA-binding domains for sequence-specific DNA recognition
    Marmorstein, R
    Fitzgerald, MX
    GENE, 2003, 304 : 1 - 12
12345