Scintigraphic imaging of paediatric thyroid dysfunction

被引：37

作者：

Clerc, J. ^{[1
]}

Monpeyssen, H. ^{[1
]}

Chevalier, A. ^{[1
]}

Amegassi, F. ^{[1
]}

Rodrigue, D. ^{[2
]}

Leger, F. A. ^{[1
]}

Richard, B. ^{[1
]}

机构：

[1] Cochin Hosp, Dept Nucl Med, F-75679 Paris 1, France

[2] Hop St Vincent de Paul, Fac Med Rene Descartes Paris 5, Dept Paediat Endocrinol, F-75674 Paris, France

来源：

HORMONE RESEARCH | 2008年 / 70卷 / 01期

关键词：

thyroid scintigraphy; congenital hypothyroidism; paediatric thyrotoxicosis; thyroid ultrasound imaging;

D O I：

10.1159/000129672

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Imaging of thyroid dysfunction is safe and clinically relevant in children. In congenital hypothyroidism (CH), thyroid imaging permits a precise characterization of the aetiology, which is important for genetic counselling and clinical management. CH may be due to thyroid dysgenesis (ectopia, hypoplasia and athyrosis) or occurs in eutopic glands. In the latter, hypothyroidism may be either transient, especially after iodine overload, or due to permanent autosomal recessive dyshormonogenesis. Thyroid scintigraphy (TS) with either (99m)TcO(4) or (123)I will identify ectopic thyroid tissue, which is the commonest cause of CH. However, recent reports favour the use of (123)I, which enhances the accuracy of the aetiological classification. In cases of eutopic thyroid, the measurement of (123)I uptake before and after perchlorate administration evaluates the organification process. At all ages, colour Doppler ultrasound scanning (CDU) is helpful in assessing thyroid volume, in identifying nodules and in characterizing tissue vascularization. TS and CDU images of most paediatric thyroid dysfunctions are presented. Copyright (C) 2008 S. Karger AG, Basel.

引用

页码：1 / 13

页数：13

共 55 条

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