Depressive Symptoms, Substance Use, and HIV-Related High-Risk Behaviors Among Opioid-Dependent Individuals: Results From the Clinical Trials Network

被引：34

作者：

Pilowsky, Daniel J. ^{[1
]}

Wu, Li-Tzy ^{[2
]}

Burchett, Bruce ^{[2
]}

Blazer, Dan G. ^{[2
]}

Ling, Walter ^{[3
]}

机构：

[1] Columbia Univ, Dept Epidemiol & Psychiat, New York, NY 10032 USA

[2] Duke Univ, Med Ctr, Sch Med, Dept Psychiat & Behav Sci, Durham, NC 27710 USA

[3] Univ Calif Los Angeles, David Geffen Sch Med, Dept Psychiat & Behav Sci, Los Angeles, CA 90095 USA

来源：

SUBSTANCE USE & MISUSE | 2011年 / 46卷 / 14期

基金：

美国国家卫生研究院;

关键词：

depression; HIV; high-risk behaviors; heroin; opiates; cocaine; amphetamines; substance abuse; substance dependence; injection drug use; INJECTION-DRUG-USERS; NEEDLE-SHARING BEHAVIOR; HEALTH SURVEY SF-36; SEXUAL RISK; TRANSMISSION RISK; UNITED-STATES; RELIABILITY; VALIDITY; ABUSE; ADOLESCENCE;

D O I：

10.3109/10826084.2011.611960

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

The sample included 343 opioid-dependent adults enrolled in two national multisite studies of the National Drug Abuse Treatment Clinical Trials Network (CTN001-002). Opioid-dependent individuals were recruited from 12 sites across the United States from January 2001 to July 2002. We examined associations between depressive symptoms, co-occurring substance use (i.e., the use of substances other than opioids), and HIV-related sexual and injection risk behaviors. Data were collected using the Addiction Severity Index and the HIV Risk Behavior Scale, and analyzed using linear regression. Depressive symptoms were associated with an increased level of injection risk behaviors but were not associated with risky sexual behaviors. The co-occurring use of amphetamines also increased the likelihood of risky sexual behaviors. The study limitations and clinical implications are noted. The study was funded by the U. S. National Institute on Drug Abuse.

引用

页码：1716 / 1725

页数：10

共 47 条

[1] Drug dependence among young recently initiated injection drug users [J].

Arria, AM ;

Fuller, C ;

Strathdee, SA ;

Latkin, C ;

Vlahov, D .

JOURNAL OF DRUG ISSUES, 2002, 32 (04) :1089-1102

[2]

Balon R., 2006, ANN CLIN PSYCHIAT, V18, P277

[3] High-risk behaviors in women who use crack: Knowledge of HIV serostatus and risk behavior [J].

Brewer, Toye H. ;

Zhao, Wei ;

Metsch, Lisa R. ;

Coltes, Amanda ;

Zenilman, Jonathan .

ANNALS OF EPIDEMIOLOGY, 2007, 17 (07) :533-539

[4]

Brown Larry K, 2006, J Adolesc Health, V39, DOI 10.1016/j.jadohealth.2006.01.015

[5]

Centers for Disease Control and Prevention (CDC), 2006, MMWR Morb Mortal Wkly Rep, V55, P273

[6] Suicide attempts prior to starting methadone maintenance treatment in Taiwan [J].

Chen, Vincent Chin-Hung ;

Lin, Tsang-Yaw ;

Lee, Charles Tzu-Chi ;

Lai, Te-Jen ;

Chen, Hong ;

Ferri, Cleusa P. ;

Gossop, Michael .

DRUG AND ALCOHOL DEPENDENCE, 2010, 109 (1-3) :139-143

[7]

COHEN P, 1984, ARCH GEN PSYCHIAT, V41, P1178

[8] Are negative affective states associated with HIV sexual risk behaviors? A meta-analytic review [J].

Crepaz, N ;

Marks, G .

HEALTH PSYCHOLOGY, 2001, 20 (04) :291-299

[9] THE RELIABILITY AND VALIDITY OF A SCALE TO MEASURE HIV RISK-TAKING BEHAVIOR AMONG INTRAVENOUS-DRUG-USERS [J].

DARKE, S ;

HALL, W ;

HEATHER, N ;

WARD, J ;

WODAK, A .

AIDS, 1991, 5 (02) :181-185

[10] High-risk behaviors associated with transition from illicit non-injection to injection drug use among adolescent and young adult drug users: a case-control study [J].

Fuller, CM ;

Vlahov, D ;

Ompad, DC ;

Shah, N ;

Arria, A ;

Strathdee, SA .

DRUG AND ALCOHOL DEPENDENCE, 2002, 66 (02) :189-198

← 1 2 3 4 5 →