Design principle in biosensing: Critical analysis based on graphitic carbon nitride (G-C3N4) photoelectrochemical biosensor

被引:91
作者
Low, Sze Shin [1 ]
Chen, Zetao [1 ]
Li, Yaru [1 ]
Lu, Yanli [1 ]
Liu, Qingjun [1 ]
机构
[1] Zhejiang Univ, Dept Biomed Engn, Biosensor Natl Special Lab, Key Lab Biomed Engn Educ Minist, Hangzhou 310027, Peoples R China
基金
中国国家自然科学基金; 中国博士后科学基金;
关键词
Graphitic carbon nitride; Photoelectrochemistry; Bioanalysis strategies; Design principle; Biosensor; ENHANCED PHOTOCATALYTIC ACTIVITY; SIGNAL AMPLIFICATION; QUANTUM DOTS; CDS-AT-G-C3N4; HETEROJUNCTION; IMMUNOSENSING PLATFORM; HYDROTHERMAL SYNTHESIS; THERMAL EXFOLIATION; HYDROGEN-PRODUCTION; FACILE SYNTHESIS; DOPED G-C3N4;
D O I
10.1016/j.trac.2021.116454
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Photoelectrochemical (PEC) biosensing has been attracting increasing attention as the generation of PEC current resulting from the biological interactions between biorecognition element and analyte has rendered PEC biosensor with high sensitivity and low detection limit. This review provides a panoramic snapshot of this dynamically developing field, with special emphasis on the design principle in biosensing, critically analyzing graphitic carbon nitride (g-C3N4)-based PEC biosensor. The basis and synthesis approaches for g-C3N4 are summarized, detailing the recent work done. This review highlights the novel concept of g-C3N4-based PEC biosensor based on three design principles: turn-on, turn-off and ratiometric, providing comprehensive design guidelines for researchers to develop more advanced PEC biosensors. Finally, future outlook and challenges for the progression of PEC biosensor are also evaluated and discussed. This work will serve as a useful and informative source for interested audience regarding the latest developments of g-C3N4-based biosensor in the field of PEC bioanalysis. (C) 2021 Elsevier B.V. All rights reserved.
引用
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页数:12
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