Synthesis of 1,4-enynes via nickel-catalyzed cross-coupling of allylic alcohols with alkynylzinc reagents

被引：5
|
作者：
He, Xue-Yi [1 ,2 ]
Wang, Zhong-Xia [1 ,2 ,3 ]
机构：
[1] Univ Sci & Technol China, CAS Key Lab Soft Matter Chem, Hefei 230026, Anhui, Peoples R China
[2] Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China
[3] Collaborat Innovat Ctr Chem Sci & Engn, Tianjin 300072, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2021年 / 57卷 / 90期
基金：
中国国家自然科学基金;
关键词：
TERMINAL ALKYNES; ALKYNYLATION; LIGAND; REGIOSELECTIVITY; IDENTIFICATION; ELECTROPHILES; COMPLEXES; ARYL;
D O I：
10.1039/d1cc05221g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Synthesis of 1,4-enynes was performed via nickel-catalyzed cross-coupling of allylic alcohols with alkynylzinc reagents. The reaction features high regio- and E/Z-selectivity when aryl-substituted allylic alcohols were employed. The method also exhibits a wide scope of substrates and good compatibility of functional groups.
引用
收藏
页码：11988 / 11991
页数：4
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