Synthesis of 1,4-enynes via nickel-catalyzed cross-coupling of allylic alcohols with alkynylzinc reagents

被引：5

作者：

He, Xue-Yi ^{[1
,2
]}

Wang, Zhong-Xia ^{[1
,2
,3
]}

机构：

[1] Univ Sci & Technol China, CAS Key Lab Soft Matter Chem, Hefei 230026, Anhui, Peoples R China

[2] Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China

[3] Collaborat Innovat Ctr Chem Sci & Engn, Tianjin 300072, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2021年 / 57卷 / 90期

基金：

中国国家自然科学基金;

关键词：

TERMINAL ALKYNES; ALKYNYLATION; LIGAND; REGIOSELECTIVITY; IDENTIFICATION; ELECTROPHILES; COMPLEXES; ARYL;

D O I：

10.1039/d1cc05221g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Synthesis of 1,4-enynes was performed via nickel-catalyzed cross-coupling of allylic alcohols with alkynylzinc reagents. The reaction features high regio- and E/Z-selectivity when aryl-substituted allylic alcohols were employed. The method also exhibits a wide scope of substrates and good compatibility of functional groups.

引用

页码：11988 / 11991

页数：4

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