Organic synthesis in water: Green protocol for the conjugate addition of thiols to p-quinones

被引：42
|
作者：
Yadav, J. S. [1 ]
Swamy, T. [1 ]
Reddy, B. V. Subba [1 ]
Rao, D. Kishna [1 ]
机构：
[1] Indian Inst Chem Technol, Div Organ Chem, Hyderabad 500007, Andhra Pradesh, India
来源：
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2007年 / 274卷 / 1-2期
关键词：
thia-Michael addition; quinones; diaryl sulfides; aryl alkyl sulfides;
D O I：
10.1016/j.molcata.2007.04.037
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The Michael addition of thiols to p-quinones proceeds efficiently in water at room temperature without a catalyst. Significant rate acceleration of this reaction is observed in water compared to organic solvents. Water played a dual role in simultaneously activating the quinones and thiols. This new methodology constitutes an easy, highly efficient and green synthesis of diaryl sulfides and aryl alkyl sulfides. (c) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码：116 / 119
页数：4
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