Quality of life in patients with coronary artery disease treated with coronary artery bypass grafting and hybrid coronary revascularization

Background: Patients with stable coronary artery disease (CAD) have a worse quality of life (QoL) in comparison to patients without stable CAD. Standardized questionnaires are used in evaluation of QoL. Hybrid coronary revascularization (HCR) is a recently-introduced, minimally invasive option for patients requiring revascularization for coronary lesions. The aim of this study was to assess health-related quality of life (HRQoL) in patients with multivessel CAD (MVCAD), according to the mode of revascularization: coronary artery bypass grafting (CABG) or HCR using the generic SF-36 v.2 questionnaire. Methods: From November 2009 to July 2012, 200 patients from POLMIDES study with diagnosed MVCAD and were referred for conventional CABG were randomized to HCR (n = 98) or CABG (n =102) groups in 1:1 ratio. HRQoL were measured at two time points: hospital admission and 12-month follow up. The primary endpoint was the difference in HRQoL after the procedure. Results: Both groups showed the same improvement of HRQoL: in HCR group: 13.5 (3.82-22.34) vs. CABG group: 10.48 (2.46-31.07); p = 0.76. Conclusions: HRQoL in patients after both modes of revascularization significantly improved after 12 months in all domains.