Immune check-point in cervical cancer

被引：50
作者：
De Felice, F. [1 ]
Marchetti, C. [2 ]
Palaia, I. [2 ]
Ostuni, R. [2 ]
Muzii, L. [2 ]
Tombolini, V. [1 ]
Panici, P. Benedetti [2 ]
机构：
[1] Sapienza Univ Rome, Dept Radiotherapy, Policlin Umberto 1, Rome, Italy
[2] Sapienza Univ Rome, Dept Gynecol & Obstet Sci & Urol Sci, Rome, Italy
来源：
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY | 2018年 / 129卷
关键词：
Cervical cancer; Immune check-point; Immunotherapy; CTLA-4; PD-1; Ipilimumab; Pembrolizumab; Nivolumab; NIVOLUMAB; RECURRENT; EFFICACY; SAFETY;
D O I：
10.1016/j.critrevonc.2018.06.006
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Despite different treatment strategies, locally advanced cervical cancer (CC) persists as one of the most incurable cancers among women worldwide. In fact, this setting of patients are at high risk of persistent and recurrent disease. In recent years, researches have investigated immune check-point inhibitors in hopes of determining improved response to therapy with prolongation of survival. We reviewed the published literature and conference proceedings and presented pivotal trials supporting immune check-point inhibitors use in the treatment of CC.
引用
收藏
页码：40 / 43
页数：4
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