Transfusion Considerations in Pediatric Hematology and Oncology Patients

被引:6
作者
Bercovitz, Rachel S. [1 ,2 ]
Josephson, Cassandra D. [3 ]
机构
[1] BloodCtr Wisconsin, Inst Med Sci, 638 North 18th St, Milwaukee, WI 53233 USA
[2] Med Coll Wisconsin, Dept Pathol & Pediat, 8701 W Watertown Plank Rd, Milwaukee, WI 53226 USA
[3] Emory Univ, Sch Med, Childrens Healthcare Atlanta, Dept Pathol & Pediat, 1405 Clifton Rd Northeast, Atlanta, GA 30322 USA
关键词
Pediatrics; Transfusions; Thrombocytopenia; Anemia; Red blood cell transfusion; Platelet transfusion; Granulocyte transfusion; BLOOD-CELL TRANSFUSION; BONE-MARROW-TRANSPLANTATION; FRESH-FROZEN PLASMA; PROPHYLACTIC GRANULOCYTE TRANSFUSIONS; ACUTE LYMPHOBLASTIC-LEUKEMIA; LUMBAR PUNCTURE; IRON OVERLOAD; VENOOCCLUSIVE DISEASE; CONTROLLED-TRIAL; INDUCTION CHEMOTHERAPY;
D O I
10.1016/j.hoc.2016.01.010
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Pediatric patients with malignancies or benign hematologic diseases are a heterogeneous group with complicated underlying pathophysiologies leading to their requirements for transfusion therapy. Common practice among pediatric hematologists, oncologists, and transplant physicians is to transfuse stable patients' red cells to maintain a hemoglobin greater than 7 or 8 g/dL and transfuse platelets to maintain a count greater than 10,000 or 20,000 platelets/pt. This review compiles data from myriad studies performed in pediatric patients to give readers the knowledge needed to make an informed choice when considering different management strategies for the transfusion of red blood cells, platelets, plasma, and granulocytes.
引用
收藏
页码:695 / +
页数:16
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