Chemistry - Synthetic lessons from quinine

被引：11

作者：

Weinreb, SM ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA

来源：

NATURE | 2001年 / 411卷 / 6836期

关键词：

Synthetic chemistry;

D O I：

10.1038/35078178

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

As the oldest, naturally occurring, treatment for malaria, quinine has been a target for synthetic chemistry for 150 years. At last, modern techniques provide full control over the synthetic molecule.

引用

页码：429 / 431

页数：3

共 7 条

[1]

Corey E.J., 1989, The Logic of Chemical Synthesis

[2] TOTAL SYNTHESIS OF CINCHONA ALKALOIDS .4. SYNTHESES VIA QUINUCLIDINE PRECURSORS [J].

GRETHE, G ;

LEE, HL ;

MITT, T ;

USKOKOVIC, MR .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (02) :589-593

[3]

Perkin W.H., 1896, J. Chem. Soc, V69, P596

[4]

ROUHI AM, 2000, CHEM ENG NEWS 0507, P54

[5] The first stereoselective total synthesis of quinine [J].

Stork, G ;

Niu, D ;

Fujimoto, A ;

Koft, ER ;

Balkovec, JM ;

Tata, JR ;

Dake, GR .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (14) :3239-3242

[6]

Verpoorte R., 1988, ALKALOIDS, V34, P331

[7]

Woodward RB, 1944, J AM CHEM SOC, V66, P849, DOI 10.1021/ja01233a516

← 1 →